journal article·2024-10Open access

Intelligent Wearable Graphene Nano‐Electronics with Switchable Surface Wettability Capabilities for Autonomous Sweat Enrichment‐Purification‐Analysis

Zhuang Hao, Xiaojie Fang, Ziran Wang, Cong Huang, Feiran Li, Yang Luo, Yuhan Ying, Shuang Ma, Yuan Jia, Xuejun Wang, Yunlu Pan

Advanced Functional Materials· Volume 34· Issue 41

Abstract

Abstract Sweat wearable biosensors facilitate continuous monitoring of individuals’ in‐depth body physiological state with real‐time and molecular‐level insight. However, limited detection accuracy and sensitivity resulted from insufficient amount of sweat sampling and impurities interferences still hinder their practical applications. Here, a miniature wearable skin‐interfaced intelligent graphene nano‐electronic (SIGN) patch employing a novel Janus membrane integrated surface wettability switchable microfluidic module with autonomous sweat sampling and purification capabilities is presented for in situ analysis of sweat biomarkers. Due to the asymmetric surface energy distribution characteristics of the microfluidic surfaces, rapid, directional transport of sufficient amount of sweat to the Janus membrane is achieved. The Janus membrane purifies the sweat sample and transport the sample to the sensing surface autonomously, thus eliminating impurities interferences and enhancing the sensing performance. An ultra‐flexible bio‐receptor functionalized graphene transistor for accurately monitoring sweat biomarkers such as lactate, with outstanding signal reproducibility and good long‐term (over 1 month) stability, and a signal processing unit are employed incorporating with the microfluidic module. In practical wearing tests, the SIGN patch enables the continuous measuring of sweat lactate levels for volunteers during exercises and intelligently providing a preliminary diagnostic assessment on their exercise intensity successfully, suggesting its potential commercialization prospects.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Advanced Sensor and Energy Harvesting Materials · Tactile and Sensory Interactions · Nanomaterials and Printing Technologies

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

School of Mechanical Engineering & Automation Beihang University Beijing 100191 China

School of Electronics and Information Engineering Harbin Institute of Technology Harbin 150001 China

Key Laboratory of High‐efficiency and Clean Mechanical Manufacture of MOE School of Mechanical Engineering Shandong University Jinan 250061 China

State Key Laboratory of Robotics and Systems School of Mechatronics Engineering Harbin Institute of Technology Harbin 150001 China

State Key Laboratory of Robotics Shenyang Institute of Automation Chinese Academy of Sciences Shenyang 110169 China

Institutes for Robotics and Intelligent Manufacturing Chinese Academy of Sciences Shenyang 110169 China

University of Chinese Academy of Sciences Beijing 100049 China

Department of Electronic Information Engineering Shenyang Aerospace University Shenyang 110034 China

Sino‐German College of Intelligent Manufacturing Shenzhen Technology University Shenzhen 518118 China

State Key Laboratory of Molecular Engineering of Polymers Fudan University Shanghai 200433 China

Funding

National Natural Science Foundation of China · China Postdoctoral Science Foundation · National Postdoctoral Program for Innovative Talents · Natural Science Foundation of Heilongjiang Province · Natural Science Foundation of Chongqing · Taishan Scholar Foundation of Shandong Province

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