journal article·2018-03-01

Nitrogen-Doped Biocompatible Carbon Dot as a Fluorescent Probe for STORM Nanoscopy

Navneet C. Verma, Chethana Rao, Chayan K. Nandi

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Abstract

Fluorescent carbon dots (CDs) have got tremendous applications in bioimaging, molecular sensing, light harvesting, photovoltaics, catalysis, and drug delivery. This is mainly due to the superior photostability, high quantum yield, aqueous solubility, and low toxicity. However, super resolution nanoscopy using CD has rarely been reported. Here, we report the super-resolution image down to ∼64 nm in the actin filament and in the self-assembled soft matter polymeric ring structure. The photon counts, on–off duty cycles, and the number of switching cycles were good enough to get such a high resolution. This opens up a new door to the realm of application of CD in live-cell nanoscopy.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Carbon and Quantum Dots Applications · Advanced Fluorescence Microscopy Techniques · Luminescence and Fluorescent Materials

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

School of Basic Sciences, Indian Institute of Technology Mandi, Mandi, Himachal Pradesh 175001, India

Funding

Council of Scientific and Industrial Research · Department of Biotechnology , Ministry of Science and Technology

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