journal article·2008-11

In situ synthesis of hybrid nanocomposite with highly order arranged amorphous metallic copper nanoparticle in poly(2-hydroxyethyl methacrylate) and its potential for blood-contact uses

Yen-Yu Liu, Dean-Mo Liu, San-Yuan Chen, Tsan-Hua Tung, Tse-Ying Liu

Acta Biomaterialia· Volume 4· Issue 6
Publisher page

Abstract

A hybrid consisting of a highly ordered nanostructure of metallic Cu(0) nanoparticles embedded in a poly(2-hydroxyethyl methacrylate) (pHEMA) matrix was successfully synthesized by in situ photopolymerization, followed by in situ chemical reduction. The evolution of an ordered nanostructure of Cu(0) showing a nearly amorphous nature is discussed, and it is proposed that it is due to a coupling interaction between the Cu precursor and the unpaired O of the COOR group, associated with water molecules, among pHEMA molecules. The hybrids showed a negative surface charge and considerable improvement in blood compatibility compared to neat pHEMA and the widely used biomaterial polysulfonate.
Source: europepmc · Quality: candidate unverified · Source record ↗

Research context

OpenAlex topics: Advanced Polymer Synthesis and Characterization · Polymer Surface Interaction Studies · Polymer Nanocomposite Synthesis and Irradiation

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

References (21)

Show source-provided references
1. Synthesis, characterization and blood compatibility of copolymers derived from polyamidoamines and vinyl acetate10.1081/MA-200050470 ↗
2. Soft contact lens biomaterials from bioinspired phospholipid polymers10.1586/17434440.3.2.167 ↗
3. Coating of cardiovascular stents with a semiconductor to improve their hemocompatibility
4. Electrochemical aspects of thrombogenicity of a material
5. Structure and blood compatibility of tetrahedral amorphous hydrogenated carbon formed by a magnetic-field-filter plasma stream10.1016/j.surfcoat.2006.09.021 ↗
6. The catastrophe revisited: blood compatibility in the 21st century10.1016/j.biomaterials.2007.07.035 ↗
7. Hemocompatibility of titanium-based coatings prepared by metal plasma immersion ion implantation and deposition10.1016/j.nimb.2006.12.169 ↗
8. Influence of plasma treatments on the hemocompatibility of PET and PET+TiO2 films10.1007/s11090-006-9046-y ↗
9. Nitric oxide-releasing fumed silica particles: synthesis, characterization, and biomedical application10.1021/ja0291538 ↗
10. The interaction of selected semiconducting biomaterials with platelet-rich plasma and whole blood10.1002/jbm.a.30255 ↗
11. Catalytic generation of nitric oxide from nitrite at the interface of polymeric films doped with lipophilic Cu(II)-complex: a potential route to the preparation of thromboresistant coatings10.1016/S0142-9612(03)00530-1 ↗
12. Improving blood compatibility of intravascular oxygen sensors via catalytic decomposition of S-nitrosothiols to generate nitric oxide in situ10.1016/j.snb.2006.09.025 ↗
13. Synthesis, structural characterization and antitumor activity evaluations of copper complex with tetraazamacrocyclic ligand10.1016/S0960-894X(99)00139-0 ↗
14. Ion exchange adsorption and membrane filtration hybrid process for protein mixture separation10.1252/jcej.39.1283 ↗
15. Fractal aggregation and optical absorption of copper nanoparticles prepared by in situ chemical reduction within a Cu2+–polymer complex10.1063/1.123657 ↗
16. Improvement in the floatability of CuO by dry grinding with sulphur10.1016/j.colsurfa.2007.03.021 ↗
17. Redox catalysis on “Naked” silver nanoparticles10.1021/jp074257w ↗
18. Hemocompatibility of treated polystyrene substrates: contact activation, platelet adhesion, and procoagulant activity of adherent platelets10.1002/(SICI)1097-4636(19980915)41:4<657::AID-JBM18>3.0.CO;2-B ↗
19. Physicochemical properties and platelet interactions of segmented polyurethanes containing sulfonate groups in the hard segment10.1002/(SICI)1097-4636(19970315)34:4<439::AID-JBM5>3.0.CO;2-L ↗
20. The reduction of oxidative stress, anticoagulation of platelets, and inhibition of lipopolysaccharide by conjugated linoleic acid bonded on a polysulfone membrane10.1002/pat.863 ↗
21. Study on blood compatibility with poly(2-methoxyethylacrylate)-relationship between surface structure, water structure, and platelet compatibility in 2-methoxyethylacrylate/2-hydroxyethylmethacrylate diblock copolymer10.1002/jbm.a.30563 ↗