Sol–gel derived aluminosilicate coatings on alumina as substrate for osteoblasts
Source abstract
Abstract
Rat bone marrow stromal cell differentiation on aluminosilicate 3Al(2)O(3)-2SiO(2) coatings was investigated. Thin ceramic coatings were prepared on alpha-alumina substrates by the sol-gel process and calcined in order to establish an amorphous aluminosilicate ceramic phase with and without nanosized transitional mullite crystals. In addition, coatings of thermally sprayed aluminosilicate and diphasic gamma-alumina-silica nanosized colloids were prepared. Cell culture testing by rat osteoblasts showed good biocompatibility for aluminosilicates with sustained normal osteoblast functions. Despite mutual disparities in physical and chemical nanostructures, the culture findings suggested fairly similar osteoblast response to all tested coatings. The results suggest that topographical frequency parameters and chemical uniformity are important parameters in determining the best conditions for osteoblasts on sol-gel derived aluminosilicate materials.
Source: europepmc · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Bone Tissue Engineering Materials · Calcium Carbonate Crystallization and Inhibition · Laser-Ablation Synthesis of Nanoparticles
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (48)
Show source-provided references
1. Coatings on Al2O3 by bioactive glass–ceramics10.1016/S1359-6454(00)00255-X ↗
2. An investigation of bioactive glass powders by sol–gel processing10.1002/jab.770020403 ↗
3. Bioceramics10.1111/j.1151-2916.1998.tb02540.x ↗
4. Biological glass coating on ceramic materials: in vitro evaluation using primary osteoblast cultures from healthy and osteopenic rat bone10.1016/S0142-9612(00)00444-0 ↗
5. Bioactivity of sol–gel bioactive glass coated alumina implants10.1002/1097-4636(200011)52:2<422::AID-JBM24>3.0.CO;2-P ↗
6. Bioactivity of CaO–SiO2 glasses added with various ions10.1007/BF00705275 ↗
7. Chemical and mechanical behavior of bioglass-coated alumina10.1002/jbm.820100405 ↗
8. Solubility and film formation of phosphate and alumina containing silicate glasses10.1016/S0022-3093(99)00072-1 ↗
9. Crystallization modifies osteoconductivity in an apatite-mullite glass–ceramic10.1023/A:1026306901058 ↗
10. Soft tissue response to four dense ceramic materials and two clinically used biomaterials10.1002/jbm.820090411 ↗
11. Osteoblast adhesion on nanophase ceramics10.1016/S0142-9612(99)00020-4 ↗
12. Increased osteoblast functions on theta+delta nanofiber alumina10.1016/j.biomaterials.2004.03.040 ↗
13. Enhanced functions of osteoblasts on nanophase ceramics10.1016/S0142-9612(00)00075-2 ↗
14. Schneider · 1994
15. Characterization of mono- and diphasic mullite precursor powders prepared by aqueous routes. 27Al and 29Si MAS NMR spectroscopy investigations10.1007/BF00366355 ↗
16. Characterization of low temperature mullitization10.1016/0955-2219(95)00131-X ↗
17. Sol–gel synthesis of a nanoparticulate aluminosilicate precursor for homogeneous mullite ceramics10.1557/jmr.2006.0152 ↗
18. Biological surface science10.1016/S0039-6028(01)01809-X ↗
19. Integrins as linker proteins between osteoblasts and bone replacing materials. A critical review10.1016/j.biomaterials.2004.02.021 ↗
20. Osteoblast adhesion on biomaterials10.1016/S0142-9612(99)00242-2 ↗
21. Statistical correlation between cell adhesion and proliferation on biocompatible metallic materials10.1002/jbm.a.30212 ↗
22. An unscaled parameter to measure the order of surfaces: a new surface elaboration to increase cells adhesion10.1016/S1389-0344(02)00048-5 ↗
23. Topography effects of pure titanium substrates on human osteoblast long-term adhesion10.1016/j.actbio.2004.11.009 ↗
24. Initial in vitro interaction of osteoblasts with nano-porous alumina10.1016/S0142-9612(03)00146-7 ↗
25. Calcium phosphate formation on porous sol–gel derived SiO2 and CaO–P2O5–SiO2 substrates in vitro10.1002/(SICI)1097-4636(199901)44:1<12::AID-JBM2>3.0.CO;2-E ↗
26. Mechanism of hydroxyapatite formation on porous gel-silica substrates10.1007/BF00401884 ↗
27. Surface properties of in vitro bioactive and non-bioactive sol–gel derived materials10.1016/S0142-9612(02)00017-0 ↗
28. Preparation by sol–gel method of SiO2 and mullite (3Al2O3, 2SiO2) powders and study of their surface characteristics by inverse gas chromatography and zetametry10.1016/S0927-7757(97)00149-0 ↗
29. Calcium phosphate formation within sol–gel-prepared titania in vitro and in vivo10.1002/jbm.820271205 ↗
30. Bone formation in vitro by stromal cells obtained from bone marrow of young adult rats
31. Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity10.1046/j.1432-1327.2000.01606.x ↗
32. Reporting physisorption data for gas/solid systems10.1351/pac198557040603 ↗
33. Optimization of surface micromorphology for enhanced osteoblast responses in vitro
34. Cell and tissue behaviour on microgrooved surfaces10.1007/s10266-001-8178-z ↗
35. Synergistic interaction of topographic features in the production of bone-like nodules on Ti surfaces by rat osteoblasts10.1016/j.biomaterials.2004.04.020 ↗
36. Relationship of cell growth to the regulation of tissue-specific gene expression during osteoblast differentiation10.1096/fasebj.4.13.2210157 ↗
37. Cellular expression of bone-related proteins during in vitro osteogenesis in rat bone marrow stromal cell cultures10.1002/jcp.1041580322 ↗
38. A new fluorometric assay for determination of osteoblastic proliferation: effects of glucocorticoids and insulin-like growth factor-I10.1007/s002239900182 ↗
39. The challenge to measure cell proliferation in two and three dimensions10.1089/ten.2005.11.182 ↗
40. Preparation of SBF with different HCO3- content and its influence on the composition of biomimetic apatites10.1016/j.actbio.2005.11.001 ↗
41. A mineralogical perspective on the apatite in bone10.1016/j.msec.2005.01.008 ↗
42. The effect of organic ligands on the crystallinity of calcium phosphate10.1016/S0022-0248(02)02227-3 ↗
43. Calcification as an indicator of osteoinductive capacity of biomaterials in osteoblastic cell cultures10.1016/j.biomaterials.2005.01.025 ↗
44. Apatite nucleation on silica surface: a ζ potential approach10.1002/1097-4636(200110)57:1<119::AID-JBM1150>3.0.CO;2-P ↗
45. Adsorption of proteins and calcium phosphate materials bioactivity10.1016/S0142-9612(02)00073-X ↗
46. Cytocompatibility of two coating materials, amorphous alumina and silicon carbide using human differentiated cell cultures10.1016/0142-9612(91)90118-T ↗
47. Aluminium stimulates the proliferation and differentiation of osteoblasts in vitro by a mechanism that is different from fluoride
48. What is wrong with aluminium? The J.D. Birchall memorial lecture10.1016/S0162-0134(99)00118-X ↗