DataVXACS NanoPaper
journal article·2026-03-24

Light-Programmable Nanograspers for Rapid Nanoplastics Detection in Biological Fluids

Wenbo Dong, Bingrui Xu, Rongxin Fu, Fan Yang, Han Cui, Zipeng Zhao, Yifan Zhang, Hang Li, Kangfu Chen, Xiaorong Hong, Jiangjiang Zhang, Xuekai Liu, Jiafang Li, Yeliang Wang, Huikai Xie, Shuailong Zhang

ACS Nano· Volume 20· Issue 11
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Source abstract

Abstract

Rapid and reliable detection of nanoplastics and other analytes in complex biological and environmental media is very important for public health management and environment protection but there is still a lack of effective methods. Here, we report optoelectronic-tweezer-assisted nanograspers (OET-NGP), a reconfigurable trapping system that dynamically assembles metallic nanoparticles into light-programmable grasping structures. This approach enables not only rapid analyte enrichment but also the formation of highly uniform hotspots with improved Surface-Enhanced Raman scattering (SERS) reproducibility, achieving a detection limit as low as 4.43 × 10 –8 M for Rhodamine B. More importantly, the OET-NGP platform enables in situ capture and SERS detection of nanoplastics at μg/mL level in both aqueous media and serum. These results highlight the capability and great promise of OET-NGP as a powerful sensing tool for effective nanoplastic detection with great potential for environmental monitoring and biosafety assessment.
Source: openalex_inverted_index · Quality: baseline

Research context

NanomaterialsElectronic materials

OpenAlex topics: Innovative Microfluidic and Catalytic Techniques Innovation · Microfluidic and Bio-sensing Technologies · Gold and Silver Nanoparticles Synthesis and Applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Beijing Advanced Innovation Center for Intelligent Robots and Systems, School of Mechatronical Engineering

Beijing Institute of Technology

School of Medical Technology

Zhengzhou Research Institute

Engineering Research Center of Integrated Acousto-optoelectronic Microsystems (Ministry of Education of China)

Chongqing Institute of Microelectronics and Microsystems, Beijing Institute of Technology

State Key Laboratory of Chips and Systems for Advanced Light Field Display, School of Optics and Photonics

School of Materials Science and Engineering

Institute of Chemistry

Chinese Academy of Sciences

State Key Laboratory of Chips and Systems for Advanced Light Field Display, School of Integrated Circuits and Electronics

School of Physics

School of Life Science

Department of Laboratory Medicine

Aerospace Center Hospital

Funding

National Key Research and Development Program of China · Science and Technology Foundation of Shenzhen City · Natural Science Foundation of Chongqing Municipality · Natural Science Foundation of Beijing Municipality · National Natural Science Foundation of China · State Key Laboratory of Optoelectronic Materials and Technologies · BIT Research and Innovation Promoting Project · State Key Laboratory of Digital Medical Engineering

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