Spatially Selecting a Single Cell for Lysis Using Light‐Induced Electric Fields
Source abstract
Abstract
An optoelectronic tweezing (OET) device, within an integrated microfluidic channel, is used to precisely select single cells for lysis among dense populations. Cells to be lysed are exposed to higher electrical fields than their neighbours by illuminating a photoconductive film underneath them. Using beam spot sizes as low as 2.5 μm, 100% lysis efficiency is reached in <1 min allowing the targeted lysis of cells.
Source: europepmc · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Microfluidic and Bio-sensing Technologies · Microfluidic and Capillary Electrophoresis Applications · Microbial Inactivation Methods
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
University of Glasgow, Division of Biomedical Engineering G12 8LT Scotland
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