DataVXACS Biomaterials Science & EngineeringPaper
journal article·2019-11-11

Metal–Organic Framework and Hydrogel Based Strategy as a Universal First-Aid Treatment of Three Different Typical Snake Bites

Ruolei Li, Fei Cao, Yutong Chen, Peixin Zhang, Chunhong Huang, Hongbo Xin, Jun Wang, Xiaolei Wang

ACS Biomaterials Science & Engineering· Volume 5· Issue 11
Publisher page
Source abstract

Abstract

Snake bite envenoming is a worldwide problem which affects the health and safety of the public. The classical antivenom methods are difficult to be used immediately and accurately. Based on this situation, a new metal–organic framework and hydrogel based first-aid treatment was first set up in this study as a facile, economic, effective, and universal alternative strategy. According to the subsequent in vitro and in vivo experiments, this dual effective (block and absorption) strategy was proven to be useful in dealing with three different representative snake venoms (Bungarus fasciatus, Protobothrops mucrosquamatus, and cobra venom).
Source: openalex_inverted_index · Quality: baseline

Research context

Polymers

OpenAlex topics: Venomous Animal Envenomation and Studies · Rabies epidemiology and control · Biochemical and Structural Characterization

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

The National Engineering Research Center for Bioengineering Drugs and the Technologies: Institition of Translational Medicine, Nanchang University, Nanchang, Jiangxi 330088, China

College of Queen Mary, Nanchang University, Nanchang, Jiangxi 330031, China

College of Resource, Environmental and Chemical Engineering, Nanchang University, Nanchang, Jiangxi 330031, China

College of Basic Medicine, Nanchang University, Nanchang, Jiangxi 330031, China

College of Chemistry, Nanchang University, Nanchang, Jiangxi 330031, China

Funding

Nanchang University · Ministry of Science and Technology of the People's Republic of China · National Natural Science Foundation of China · Science Foundation of Jiangxi Provincial Department of Education

References (38)

Show source-provided references
1. Chippaux J. P. · Bull. World Heal. Organ. · 1998 · 76 · 515
2. 10.1016/S0140-6736(09)61754-210.1016/S0140-6736(09)61754-2 ↗
3. 10.1038/nrdp.2017.6310.1038/nrdp.2017.63 ↗
4. 10.1016/S0195-5616(93)50152-310.1016/S0195-5616(93)50152-3 ↗
5. 10.1371/journal.pntd.000167010.1371/journal.pntd.0001670 ↗
6. 10.1016/j.toxicon.2018.06.08410.1016/j.toxicon.2018.06.084 ↗
7. 10.1016/j.toxicon.2019.06.04410.1016/j.toxicon.2019.06.044 ↗
8. 10.1016/S0041-0101(96)00193-610.1016/S0041-0101(96)00193-6 ↗
9. 10.1016/j.toxicon.2006.11.02010.1016/j.toxicon.2006.11.020 ↗
10. 10.1038/s42003-018-0039-110.1038/s42003-018-0039-1 ↗
11. 10.1021/jacs.6b1095010.1021/jacs.6b10950 ↗
12. 10.1371/journal.pntd.000673610.1371/journal.pntd.0006736 ↗
13. 10.1080/0013930730943551710.1080/00139307309435517 ↗
14. 10.1021/acsbiomaterials.6b0017610.1021/acsbiomaterials.6b00176 ↗
15. 10.1021/acsbiomaterials.8b0003110.1021/acsbiomaterials.8b00031 ↗
16. 10.1021/acsbiomaterials.8b0092910.1021/acsbiomaterials.8b00929 ↗
17. 10.1002/adma.20180020210.1002/adma.201800202 ↗
18. 10.1039/C2CC35561B10.1039/C2CC35561B ↗
19. 10.1039/C8RA10619C10.1039/C8RA10619C ↗
20. 10.1002/adma.20170467910.1002/adma.201704679 ↗
21. 10.1039/C8SC04160A10.1039/C8SC04160A ↗
22. 10.1021/jacs.8b1270510.1021/jacs.8b12705 ↗
23. 10.1002/advs.20180168410.1002/advs.201801684 ↗
24. 10.1002/adma.20170736510.1002/adma.201707365 ↗
25. Iyaniwura T. T. · Vet. Hum. Toxicol. · 1991 · 33 · 468
26. 10.1007/s00018-009-0050-210.1007/s00018-009-0050-2 ↗
27. 10.1021/bi00264a02810.1021/bi00264a028 ↗
28. 10.1016/j.jprot.2012.08.00810.1016/j.jprot.2012.08.008 ↗
29. 10.1074/mcp.M115.05652310.1074/mcp.M115.056523 ↗
30. 10.1021/ja01269a02310.1021/ja01269a023 ↗
31. 10.1016/0742-8413(90)90089-R10.1016/0742-8413(90)90089-R ↗
32. Liu S. · Indian J. Exp. Biol. · 2010 · 48 · 778
33. 10.1021/cr200304e10.1021/cr200304e ↗
34. 10.2174/138161282266616062307343810.2174/1381612822666160623073438 ↗
35. Wei J. F. · Chin. J. Pathophysiol. · 2006 · 22 · 251
36. 10.1155/2017/659282010.1155/2017/6592820 ↗
37. 10.1038/nnano.2008.40210.1038/nnano.2008.402 ↗
38. Mocan T. · Mol. Biol. Nanomed. · 2013 · 1 · 7