journal article·2019-10-14

Polymer–Mineral Composites Mimic Human Kidney Stones in Laser Lithotripsy Experiments

Derek S. Frank, Ali H. Aldoukhi, William W. Roberts, Khurshid R. Ghani, Adam J. Matzger

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Abstract

Despite the widespread use of laser lithotripsy to fragment kidney stones in vivo, there is a lack of robust artificial stone models to replicate the behavior of human stones during lithotripsy procedures. This need for accurate stone models is particularly important as novel laser technologies are introduced in the field of lithotripsy. In this work, we present a method to prepare composite materials that replicate the properties of human kidney stones during laser lithotripsy. Their behavior is understood through the lens of near-IR spectroscopy and helps to elucidate the mechanism of laser lithotripsy in kidney stone materials.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Kidney Stones and Urolithiasis Treatments · Pediatric Urology and Nephrology Studies · Radioactive element chemistry and processing

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Chemistry and the Macromolecular Science & Engineering Program, University of Michigan, 930 North University, Ann Arbor, Michigan 48109, United States

Division of Endourology, Department of Urology, University of Michigan, 1500 East Medical Central Drive, SPC 5330, Ann Arbor, Michigan 48109, United States

Department of Biomedical Engineering, University of Michigan, 2200 Bonisteel Boulevard, Ann Arbor, Michigan 48109, United States

Funding

Boston Scientific Corporation

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