journal article·2015-08-10Open access

Can Cobalt(II) and Chromium(III) Ions Released from Joint Prostheses Influence the Friction Coefficient?

Y. S. Hedberg, M. Pettersson, S. Pradhan, I. Odnevall Wallinder, M.W. Rutland, C. Persson

Abstract

Cobalt chromium molybdenum alloys (CoCrMo) are commonly used as articulating components in joint prostheses. In this tribocorrosive environment, wear debris and metal ionic species are released and interact with proteins, possibly resulting in protein aggregation. This study aimed to investigate whether this could have an effect on the friction coefficient in a typical material couple, namely CoCrMo-on-polyethylene. It was confirmed that both Co(II) and Cr(III) ions, and their combination, at concentrations relevant for the metal release situation, resulted in protein aggregation and its concomitant precipitation, which increased the friction coefficient. Future studies should identify the clinical importance of these findings.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Orthopaedic implants and arthroplasty · Orthopedic Infections and Treatments · Advanced materials and composites

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Division of Surface and Corrosion Science, Department of Chemistry, School of Chemical Science and Engineering, KTH Royal Institute of Technology, Drottning Kristinas väg 51, SE-10044 Stockholm, Sweden

Unit of Occupational and Environmental Dermatology, Institute of Environmental Medicine, Karolinska Institutet, SE-17177 Stockholm, Sweden

Division of Applied Materials Science, Department of Engineering Sciences, Uppsala University, 75121 Uppsala, Sweden

Chemistry, Materials and Surfaces, SP Technical Research Institute of Sweden, SE-114 86 Stockholm, Sweden

Funding

Kungliga Tekniska H?gskolan · Seventh Framework Programme · Vetenskapsr?det

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