DataVXACS Biomaterials Science & EngineeringPaper
journal article·2022-06-13Open access

Gelatin and Tannic Acid Based Iongels for Muscle Activity Recording and Stimulation Electrodes

Ana Aguzin, Gisela C. Luque, Ludmila I. Ronco, Isabel del Agua, Gregorio Guzmán-González, Bastien Marchiori, Agustina Gugliotta, Liliana C. Tomé, Luis M. Gugliotta, David Mecerreyes, Roque J. Minari

ACS Biomaterials Science & Engineering· Volume 8· Issue 6
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Source abstract

Abstract

Iongels are soft ionic conducting materials, usually composed of polymer networks swollen with ionic liquids (ILs), which are being investigated for applications ranging from energy to bioelectronics. The employment of iongels in bioelectronic devices such as bioelectrodes or body sensors has been limited by the lack of biocompatibility of the ILs and/or polymer matrices. In this work, we present iongels prepared from solely biocompatible materials: (i) a biobased polymer network containing tannic acid as a cross-linker in a gelatin matrix and (ii) three different biocompatible cholinium carboxylate ionic liquids. The resulting iongels are flexible and elastic with Young‘s modulus between 11.3 and 28.9 kPa. The morphology of the iongels is based on a dual polymer network system formed by both chemical bonding due to the reaction of the gelatin’s amines with the polyphenol units and physical interactions between the tannic acid and the gelatin. These biocompatible iongels presented high ionic conductivity values, from 0.003 and up to 0.015 S·cm–1 at room temperature. Furthermore, they showed excellent performance as a conducting gel in electrodes for electromyography and electrocardiogram recording as well as muscle stimulation.
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Research context

PolymersBiomaterials

OpenAlex topics: Advanced Sensor and Energy Harvesting Materials · Conducting polymers and applications · Electrochemical sensors and biosensors

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Instituto de Desarrollo Tecnológico para la Industria Química (INTEC), CONICET, Güemes 3450, Santa Fe 3000, Argentina

Facultad de Ingeniería Química, Universidad Nacional del Litoral, Santiago del Estero 2829, Santa Fe 3000, Argentina

Panaxium SAS, Aix-en-Provence 13100, France

POLYMAT University of the Basque Country UPV/EHU, Joxe Mari Korta Center, Avda. Tolosa 72, 20018 Donostia-San Sebastian, Spain

UNL, CONICET, FBCB (School of Biochemistry and Biological Sciences), CBL (Biotechnological Center of Litoral), Ciudad Universitaria, Ruta Nacional 168 Km 472.4, C.C. 242., S3000ZAA Santa Fe, Argentina

LAQV-REQUIMTE, Department of Chemistry, NOVA School of Science and Technology, FCT NOVA, Universidade NOVA de Lisboa, 2829-516 Caparica, Portugal

Ikerbasque, Basque Foundation for Science, 48013 Bilbao, Spain

Funding

Universidad Nacional del Litoral · Consejo Nacional de Investigaciones Cient?ficas y T?cnicas · H2020 Marie Sklodowska-Curie Actions · Fondo para la Investigaci?n Cient?fica y Tecnol?gica

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