DataVXACS Biomaterials Science & EngineeringPaper
journal article·2021-04-12

Design and Compressive Fatigue Properties of Irregular Porous Scaffolds for Orthopedics Fabricated Using Selective Laser Melting

Lei Zhu, Huixin Liang, Fei Lv, Deqiao Xie, Changjiang Wang, Yuyi Mao, Youwen Yang, Zongjun Tian, Lida Shen

ACS Biomaterials Science & Engineering· Volume 7· Issue 4
Publisher page
Source abstract

Abstract

An irregular porous structure plays a major role in bone tissue engineering, and it is more suitable for bone tissue growth than a regular porous structure. The response surface method was used to establish a relationship between the average pore size and the design parameters. The technology of selective laser melting was utilized to fabricate the porous Ti-6Al-4V scaffolds with an irregularity of (0.4) and porosities of (70, 80, and 90%) designed using the Voronoi-tessellation method. Compression tests of porous scaffolds showed an elastic modulus range of 0.84–1.97 GPa and an ultimate strength ranging within 21.0–99.1 MPa. The elastic modulus was mainly influenced by the porosity and heat-treatment process. Furthermore, the fatigue test results suggested that the number of cycles (9 × 104 to 1.8 × 106) was greatly influenced by the porosity and heat-treatment process. The heat treatment of annealing greatly improved the fatigue performance of porous scaffolds. The irregular porous scaffolds with lower porosity and after full annealing exhibited the best fatigue behavior.
Source: openalex_inverted_index · Quality: baseline

Research context

BiomaterialsMaterials processing

OpenAlex topics: Additive Manufacturing Materials and Processes · Bone Tissue Engineering Materials · Additive Manufacturing and 3D Printing Technologies

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

College of Mechanical and Electrical Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, China

Suzhou Yunzhi Medical Technology Company, Ltd., Suzhou 215600, China

State Key Laboratory of Pharmaceutical Biotechnology, Department of Sports Medicine and Adult Reconstructive Surgery, Drum Tower Hospital Affiliated to Medical School of Nanjing University, Nanjing 210008, China

Jiangsu Engineering Research Center for 3D Bioprinting, Nanjing 210008, China

Department of Engineering and Design, University of Sussex, Brighton BN1 9RH, U.K.

National Center of Supervision and Inspection on Additive Manufacturing Products Quality, Wuxi 214028, China

Jiangxi University of Science and Technology, Ganzhou 341000, China

Funding

Ministry of Science and Technology of the People's Republic of China · China Postdoctoral Science Foundation · Government of Jiangsu Province · Jiangsu Science and Technology Department · National Natural Science Foundation of China

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