journal article·2017-06-12

Metal-Containing Poly(ionic liquid) Membranes for Antibacterial Applications

Zhiqiang Zheng, Jiangna Guo, Hailei Mao, Qiming Xu, Jing Qin, Feng Yan

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Abstract

Imidazolium-type metal-containing ionic liquid (IL) monomers and their corresponding poly(ionic liquid) (PIL) membranes coordinated with CuCl 2 (PILM-Cu), FeCl 3 (PILM-Fe), or ZnCl 2 (PILM-Zn) were synthesized. The effect of metal ions on the antimicrobial activities against both Staphylococcus aureus ( S. aureus ) and Escherichia coli ( E. coli ) was investigated. Compared with pristine PILM-Br membrane, PILM-Cu, PILM-Fe, and PILM-Zn membranes exhibit enhanced antibacterial activities due to the attributes of both imidazolium cations and metal-containing anions. Furthermore, all of the metal-containing PIL membranes present low hemolysis toward human red blood cell and high long-term antibacterial stability, even after immersion in water for 90 days, demonstrating clinical feasibility in topical applications.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Nanoparticles: synthesis and applications · Antimicrobial agents and applications · Ionic liquids properties and applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application, Department of Polymer Science and Engineering, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou, 215123, China

Department of Anesthesiology and Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai, 200032, China

Funding

National Natural Science Foundation of China · Priority Academic Program Development of Jiangsu Higher Education Institutions

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