journal article·2023-06-12

Surface Modification of Titanium Implants by Metal Ions and Nanoparticles for Biomedical Application

Nan Wu, Hongyu Gao, Xu Wang, Xibo Pei

Publisher page

Abstract

Implant surface modification can improve osseointegration and reduce peri-implant inflammation. Implant surfaces are modified with metals because of their excellent mechanical properties and significant functions. Metal surface modification is divided into metal ions and nanoparticle surface modification. These two methods function by adding a finishing metal to the surface of the implant, and both play a role in promoting osteogenic, angiogenic, and antibacterial properties. Based on this, the nanostructural surface changes confer stronger antibacterial and cellular affinity to the implant surface. The current paper reviews the forms, mechanisms, and applications of nanoparticles and metal ion modifications to provide a foundation for the surface modification of implants.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Bone Tissue Engineering Materials · Nanoparticles: synthesis and applications · Graphene and Nanomaterials Applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Department of Prosthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan 610041, China

Funding

Department of Science and Technology of Sichuan Province · National Natural Science Foundation of China

References (100+)

Show source-provided references
1. 10.1016/j.colsurfb.2021.11205510.1016/j.colsurfb.2021.112055 ↗
2. Ottria L. · J. Biol. Regul. Homeost. Agents · 2018 · 32 · 81
3. 10.21519/0234-2758-2020-36-5-31-4010.21519/0234-2758-2020-36-5-31-40 ↗
4. 10.1016/j.actbio.2019.05.04510.1016/j.actbio.2019.05.045 ↗
5. 10.3390/jcm1008164110.3390/jcm10081641 ↗
6. 10.1016/j.jcms.2017.12.02110.1016/j.jcms.2017.12.021 ↗
7. 10.1002/jbm.b.3483510.1002/jbm.b.34835 ↗
8. 10.1002/jbm.b.3468810.1002/jbm.b.34688 ↗
9. 10.1186/s11671-021-03602-210.1186/s11671-021-03602-2 ↗
10. 10.1002/jbm.a.3020410.1002/jbm.a.30204 ↗
11. 10.3390/coatings1006056810.3390/coatings10060568 ↗
12. 10.1016/j.cis.2021.10255110.1016/j.cis.2021.102551 ↗
13. 10.1002/jbm.a.3670710.1002/jbm.a.36707 ↗
14. 10.1039/D0TB01577F10.1039/D0TB01577F ↗
15. 10.1002/jbm.a.3625810.1002/jbm.a.36258 ↗
16. 10.1007/s10544-021-00573-010.1007/s10544-021-00573-0 ↗
17. 10.1002/advs.20200080010.1002/advs.202000800 ↗
18. 10.1021/acsbiomaterials.8b0050110.1021/acsbiomaterials.8b00501 ↗
19. 10.1016/j.biomaterials.2014.05.07410.1016/j.biomaterials.2014.05.074 ↗
20. 10.1021/acsnano.2c0720010.1021/acsnano.2c07200 ↗
21. 10.1016/j.dental.2017.08.19310.1016/j.dental.2017.08.193 ↗
22. 10.1007/s40820-015-0040-x10.1007/s40820-015-0040-x ↗
23. 10.1016/j.jare.2017.10.00810.1016/j.jare.2017.10.008 ↗
24. 10.3762/bjnano.9.9810.3762/bjnano.9.98 ↗
25. 10.1007/s10856-019-6221-210.1007/s10856-019-6221-2 ↗
26. 10.3390/ijms1801012010.3390/ijms18010120 ↗
27. 10.1177/204173141879069410.1177/2041731418790694 ↗
28. 10.1016/j.bioactmat.2022.03.00410.1016/j.bioactmat.2022.03.004 ↗
29. 10.1002/smtd.20200092010.1002/smtd.202000920 ↗
30. 10.1016/j.biomaterials.2018.01.04810.1016/j.biomaterials.2018.01.048 ↗
31. 10.1016/j.actbio.2018.10.03610.1016/j.actbio.2018.10.036 ↗
32. 10.1002/adfm.20191002110.1002/adfm.201910021 ↗
33. 10.1016/j.actbio.2021.05.00710.1016/j.actbio.2021.05.007 ↗
34. 10.1016/j.actbio.2020.02.03610.1016/j.actbio.2020.02.036 ↗
35. 10.2174/156802662066620112616343610.2174/1568026620666201126163436 ↗
36. 10.1039/C4TB00923A10.1039/C4TB00923A ↗
37. 10.1007/s10911-006-9003-710.1007/s10911-006-9003-7 ↗
38. 10.3389/fbioe.2020.62062910.3389/fbioe.2020.620629 ↗
39. 10.1016/j.msec.2021.11198110.1016/j.msec.2021.111981 ↗
40. 10.1039/C6MT00176A10.1039/C6MT00176A ↗
41. 10.1007/s10534-012-9528-810.1007/s10534-012-9528-8 ↗
42. 10.2174/156802661666616071516421210.2174/1568026616666160715164212 ↗
43. 10.1002/iub.234110.1002/iub.2341 ↗
44. 10.1111/j.1365-3164.2006.00551.x10.1111/j.1365-3164.2006.00551.x ↗
45. 10.1126/science.284.5415.80510.1126/science.284.5415.805 ↗
46. 10.1007/s12011-018-1583-810.1007/s12011-018-1583-8 ↗
47. 10.1159/00017777410.1159/000177774 ↗
48. 10.1111/jam.1368110.1111/jam.13681 ↗
49. 10.1021/acsbiomaterials.8b0050110.1021/acsbiomaterials.8b00501 ↗
50. 10.1007/s10856-019-6286-y10.1007/s10856-019-6286-y ↗
51. 10.3390/antibiotics910071610.3390/antibiotics9100716 ↗
52. 10.1016/j.matchemphys.2021.12543610.1016/j.matchemphys.2021.125436 ↗
53. 10.1016/j.msec.2017.08.06110.1016/j.msec.2017.08.061 ↗
54. 10.1007/s11010-011-0852-z10.1007/s11010-011-0852-z ↗
55. 10.1016/0006-2952(94)90160-010.1016/0006-2952(94)90160-0 ↗
56. 10.1007/BF0092573710.1007/BF00925737 ↗
57. 10.1016/0196-9781(95)00067-T10.1016/0196-9781(95)00067-T ↗
58. 10.1080/21691401.2018.154618710.1080/21691401.2018.1546187 ↗
59. 10.1016/j.sdentj.2018.06.00310.1016/j.sdentj.2018.06.003 ↗
60. 10.1186/s11671-020-03418-610.1186/s11671-020-03418-6 ↗
61. 10.1016/j.pnsc.2008.01.02610.1016/j.pnsc.2008.01.026 ↗
62. 10.1166/jnn.2020.1870710.1166/jnn.2020.18707 ↗
63. 10.1166/nnl.2018.282110.1166/nnl.2018.2821 ↗
64. 10.1007/s11010-008-9731-710.1007/s11010-008-9731-7 ↗
65. 10.1016/j.colsurfb.2016.08.02310.1016/j.colsurfb.2016.08.023 ↗
66. 10.1089/jir.2020.020910.1089/jir.2020.0209 ↗
67. 10.1002/2211-5463.1239910.1002/2211-5463.12399 ↗
68. 10.1016/j.bioactmat.2020.07.01210.1016/j.bioactmat.2020.07.012 ↗
69. 10.1016/j.apmt.2021.10122510.1016/j.apmt.2021.101225 ↗
70. 10.1039/D0RA01465F10.1039/D0RA01465F ↗
71. 10.1016/j.msec.2019.11006510.1016/j.msec.2019.110065 ↗
72. 10.1016/j.surfcoat.2020.12584810.1016/j.surfcoat.2020.125848 ↗
73. 10.1053/j.ackd.2018.03.00210.1053/j.ackd.2018.03.002 ↗
74. 10.1016/j.biomaterials.2020.11982810.1016/j.biomaterials.2020.119828 ↗
75. 10.1021/acsbiomaterials.0c0092910.1021/acsbiomaterials.0c00929 ↗
76. 10.1002/JPER.20-016210.1002/JPER.20-0162 ↗
77. 10.1002/advs.20190244310.1002/advs.201902443 ↗
78. 10.1002/jbm.a.3681310.1002/jbm.a.36813 ↗
79. 10.1016/j.biomaterials.2019.01.01310.1016/j.biomaterials.2019.01.013 ↗
80. 10.1038/srep4075510.1038/srep40755 ↗
81. 10.1016/j.jmst.2020.05.02510.1016/j.jmst.2020.05.025 ↗
82. 10.1093/rb/rbab01610.1093/rb/rbab016 ↗
83. 10.3389/fbioe.2022.94110910.3389/fbioe.2022.941109 ↗
84. 10.1016/j.biomaterials.2014.04.10110.1016/j.biomaterials.2014.04.101 ↗
85. 10.1557/jmr.2018.9910.1557/jmr.2018.99 ↗
86. 10.1007/s10856-019-6308-910.1007/s10856-019-6308-9 ↗
87. 10.1038/s41598-019-50496-310.1038/s41598-019-50496-3 ↗
88. 10.1007/s10856-012-4596-410.1007/s10856-012-4596-4 ↗
89. 10.2217/nnm-2018-041310.2217/nnm-2018-0413 ↗
90. 10.3892/mmr.2015.331110.3892/mmr.2015.3311 ↗
91. 10.3389/fmats.2021.73907110.3389/fmats.2021.739071 ↗
92. 10.1371/journal.pone.014066910.1371/journal.pone.0140669 ↗
93. 10.1557/jmr.2020.10710.1557/jmr.2020.107 ↗
94. 10.1016/j.colsurfb.2017.01.04710.1016/j.colsurfb.2017.01.047 ↗
95. 10.2147/IJN.S24676410.2147/IJN.S246764 ↗
96. 10.2147/IJN.S18929510.2147/IJN.S189295 ↗
97. 10.1002/adhm.20170150310.1002/adhm.201701503 ↗
98. 10.1016/j.watres.2008.12.00210.1016/j.watres.2008.12.002 ↗
99. 10.5606/ehc.2021.7935710.5606/ehc.2021.79357 ↗
100. 10.1038/s41598-022-23322-610.1038/s41598-022-23322-6 ↗