Selective and sensitive detection of metal ions by plasmonic resonance energy transfer-based nanospectroscopy
Source abstract
Abstract
Highly selective and sensitive optical methods for the detection of metal ions have had a substantial impact on molecular biology, environmental monitoring and other areas of research. Here we demonstrate a new method for detecting metal ions that is based on selective plasmonic resonance energy transfer (PRET) between conjugated metal-ligand complexes and a single gold nanoplasmonic probe. In addition to offering high spatial resolution due to the small size of the probe, our method is 100 to 1,000 times more sensitive than organic reporter-based methods. Moreover, it can achieve high selectivity owing to the selective formation of Cu(2+) complexes and selective resonant quenching of the gold nanoplasmonic probe by the conjugated complexes. We expect that PRET-based metal ion sensing could have applications in cellular imaging, systems biology and environmental monitoring.
Source: europepmc · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Advanced biosensing and bioanalysis techniques · Electrochemical Analysis and Applications · Gold and Silver Nanoparticles Synthesis and Applications
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (26)
Show source-provided references
1. Lippard, S. J. & Berg, J. M. Principle of Bioinorganic Chemistry (University Science Books, 1994).
2. Tsien, R. W. & Tsien, R. Y. Calcium channels, stores, and oscillations. Annu. Rev. Cell Biol. 6, 715–760 (1990).10.1146/annurev.cb.06.110190.003435 ↗
3. Chang, C. J., Jaworski, J., Nolan, E. M., Sheng, M. & Lippard, S. J. A tautomeric zinc sensor for ratiometric fluorescence imaing: application to nitric oxide-induced release of intracellular zinc. Proc. Natl Acad. Soc. USA 101, 1129–1134 (2004).10.1073/pnas.0308079100 ↗
4. Coronado, E. et al. Reversible colourimetric probes for mercury sensing. J. Am. Chem. Soc. 127, 12351–12356 (2005).10.1021/ja0517724 ↗
5. Ros-Lis, J. V., Marcos, M. D., Martinez-Manez, R., Rurack, K. & Soto, J. A regenerative chemodosimeter based on metal-induced dye formation for the highly selective and sensitivie optical determination of Hg2+ ions. Angew. Chem. Int. Ed. 44, 4405–4407 (2005).10.1002/anie.200500583 ↗
6. Zhu, X.-J., Fu, S.-T., Wong, W.-K., Guo, J.-P. & Wong, W.-Y. A near-infrared-fluorescent chemodosimeter for mercuric ion based on an expanded porphyrin. Angew. Chem. Int. Ed. 45, 3150–3154 (2006).10.1002/anie.200600248 ↗
7. Mancin, F., Rampazzo, E., Tecilla, P. & Tonellato, U. Self-assembled fluorescent chemosensors. Chem. Eur. J. 12, 1844–1854 (2006).10.1002/chem.200500549 ↗
8. Krämer, R. Fluorescent chemosensors for Cu2+ ions: fast, selective, and highly sensitive. Angew. Chem. Int. Ed. 37, 772–773 (1998).10.1002/(SICI)1521-3773(19980403)37:6<772::AID-ANIE772>3.0.CO;2-Z ↗
9. Kim, Y., Johnson, R. C. & Hupp, J. T. Gold nanoparticle-based sensing of “spectroscopically silent” heavy metal ions. Nano Lett. 1, 165–167 (2001).10.1021/nl0100116 ↗
10. Lee, J.-S., Han, M. S. & Mirkin, C. A. Colourimetric detection of mercuric ion (Hg2+) in aqueous media using DNA-functionalized gold nanoparticles. Angew. Chem. Int. Ed. 46, 4093–4096 (2007).10.1002/anie.200700269 ↗
11. Liu, G. L., Long, Y., Choi, Y., Kang, T. & Lee, L. P. Nanoscopic biomolecular absorption spectroscopy enabled by single nanoparticle plasmon resonance energy transfer. Nature Methods 4, 1015–1017 (2007).10.1038/nmeth1133 ↗
12. Gaggelli, E., Kozlowski, H., Valensin, D. & Valensin, G. Copper homeostasis and neurodegenerative disorders (Alzheimer's, Prion, and Parkinson's diseases and amyotrophic lateral sclerosis). Chem. Rev. 106, 1995–2004 (2006).10.1021/cr040410w ↗
13. Jun, S. & Saxena, S. The aggregated state of amyloid-β peptide in vitro depends on Cu2+ ion concentration. Angew. Chem. Int. Ed. 47, 3959–3961 (2007).10.1002/anie.200700318 ↗
14. Huang, X. et al. Cu(ii) potentiation of Alzheimer A β neurotoxicity. J. Biol. Chem. 274, 37111–37116 (1999).10.1074/jbc.274.52.37111 ↗
15. Brown, D. R. et al. The cellular prion protein binds copper in vivo. Nature 390, 684–687 (1997).10.1038/37783 ↗
16. Que, E. L. & Chang, C. J. A smart magnetic resonance contrast agent for selective copper sensing. J. Am. Chem. Soc. 128, 15942–15943 (2006).10.1021/ja065264l ↗
17. Zheng, Y. et al. Development of fluorescent film sensors for the detection of divalent copper. J. Am. Chem. Soc. 125, 2680–2686 (2003).10.1021/ja0293610 ↗
18. Klein, G., Kaufmann, D., Schürch, S. & Reymond, J.-L. A fluorescent metal sensor based on macrocyclic chelation. Chem. Commun. 561–562 (2001).10.1039/b100535i ↗
19. Smith, R. M. & Martell, A. E. Critical Stability Constants (Plenum, 1975).10.1007/978-1-4613-4452-0 ↗
20. Childs, W. R. & Nuzzo, R. G. Large-area patterning of coinage-metal thin films using decal transfer lithography. Langmuir 21, 195–202 (2005).10.1021/la047884a ↗
21. Liu, G. L. et al. Molecular ruler for measuring nuclease activity and DNA footprinting. Nature Nanotech. 1, 47–52 (2006)10.1038/nnano.2006.51 ↗
22. Rascheke, G. et al. Biomolecular recognition based on single gold nanoparticle light scattering. Nano Lett. 3, 935–938 (2003).10.1021/nl034223+ ↗
23. Andrew, P. & Barnes, W. L. Energy transfer across a metal film mediated by surface plasmon polaritons. Science 306, 1002–1005 (2004).10.1126/science.1102992 ↗
24. Van Duyne, R. P. Molecular plasmonics. Science 306, 985–986 (2004).10.1126/science.1104976 ↗
25. Zhao, J. et al. Resonance surface plasmon spectroscopy: low molecular weight substrate binding to cytochrome P450. J. Am. Chem. Soc. 128, 11004–11005 (2006).10.1021/ja0636082 ↗
26. Romero, M. J., Lagemaat, J. v. d., Mora-Sero, I., Rumbles, G. & Al-Jassim, M. M. Imaging of resonant quenching of surface plasmons by quantum dots. Nano Lett. 6, 2833–2837 (2006).10.1021/nl061997s ↗