Regenerable Biocidal Surfaces Enabled by Self-Assembled Block Copolymer Polyelectrolytes
Source abstract
Abstract
-PTHPMA thin films self-assemble into lamellae oriented parallel to the substrate, with the biocidal PQDMAEMA block forming the outermost surface layer. Mild hydrolysis converts the hydrophobic THPMA units into hydrophilic methacrylic acid moieties, rendering the copolymer water-soluble and enabling its layer-by-layer removal, renewing the active antibacterial surface. Structural ordering of the diblock copolymers is confirmed by optical and atomic force microscopy, X-ray reflectivity, and grazing incidence small-angle X-ray scattering. The film's self-polishing behavior in water is monitored by ellipsometry for 300 days. The annealed films exhibit effective and durable antibacterial activity, achieving ∼2-log reduction against both Gram-positive and Gram-negative bacteria, both annealed and after 30 days of immersion in pH 7.4 water, demonstrating sustained long-term antimicrobial performance.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Antimicrobial agents and applications · Polymer Surface Interaction Studies · Advanced Polymer Synthesis and Characterization
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Materials Science and Engineering
University of Crete
Institute of Electronic Structure and Laser
Foundation for Research and Technology − Hellas
Institut Laue Langevin (ILL), 71 Avenue des Martyrs, 38000 Grenoble, France
Heinz Maier-Leibnitz Zentrum (MLZ), Technical University of Munich, Lichtenbergstr. 1, 85748 Garching, Germany
Department of Chemistry
TUM School of Natural Sciences, Department of Physics, Chair for Functional Materials, Technical University of Munich, James-Franck-Str. 1, 85748 Garching, Germany
Funding
Bundesministerium f?r Forschung, Technologie und Raumfahrt · European Commission · European Social Fund Plus
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