Response to Comments on “Monoclonal Antibody Discovery Based on Precise Selection of Single Transgenic Hybridomas with an On-Cell-Surface and Antigen-Specific Anchor”
Source abstract
Abstract
Listek et al. described some technical concerns for the single transgenic hybridoma selection method (STHSM) that we developed. In this work, we developed the STHSM to screen hapten-specific hybridoma cells based on a streptavidin-labeled antigen originally proposed by Listek et al. that was used for the selection of OVA-specific hybridoma. Due to the obvious differences between hapten with a single epitope and protein with multiple epitopes, we significantly innovated the specific procedures in the STHSM that could answer the questions raised by Listek's group.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Monoclonal and Polyclonal Antibodies Research · Viral Infectious Diseases and Gene Expression in Insects
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
National Key Laboratory of Veterinary Public Health Security, Beijing Key Laboratory of Detection Technology for Animal Derived Food Safety, College of Veterinary Medicine, China Agricultural University, Beijing 100193, People’s Republic of China
Key Laboratory of Applied Technology on Green-Eco-Healthy Animal Husbandry of Zhejiang Province, College of Animal Science and Technology, College of Veterinary Medicine, Zhejiang A&F University, Hangzhou 311300, People’s Republic of China
References (8)
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