Forum on Materials and Interfaces in Regenerative Medicine

RecommendationsC ells can sense the complex biophysical and biochemical signals that are present in their surrounding extracellular matrix environment.Correspondingly, the ability to design and engineer a cell microenvironment provides the chance for one to orchestrate cell and tissue fates for in vitro and in vivo applications, ranging from the derivation of functional organoids that faithfully recapitulate in vivo features to serving as in vitro models to assess/predict the efficacy of novel cell and gene therapies to in vivo tissue regeneration outcomes.This Forum issue on Materials and Interfaces in Regenerative Medicine captures the recent advances in the design of biomaterials and biomaterial interfaces to recapitulate the intricate cell-microenvironment interfacial interactions.It ranges from novel designs of biocompatible and instructive materials to carefully engineered biologically relevant architecture, topography, stiffness, and biochemical signaling, as well as advanced biofabrication technologies.This Forum contains 13 papers in total, including two Review articles.