journal article·2025-07-02

Rational Design of Nanozymes for Tumor Therapy─A Perspective

Huihai Zhong, Kexuan Nie, Manman Zheng, Yujie Wang, Guohui Nie, Bin Zhang

ACS Applied Materials & Interfaces· Volume 17· Issue 26
Publisher page

Abstract

Nanozymes are nanomaterials with enzyme-like activities and have become a research hotspot in tumor therapy due to their exceptional properties. However, biological application of nanozymes remains a methodology and safety issue. More systematic and rational design of nanozymes is needed for better tumor treatment. In this Perspective, we focus on the key questions that need to be addressed in nanozyme research, including the catalytic mechanism elucidation and the construction of structure-activity relationship, and introduce several promising rational design methods as well as prospect the future development of nanozymes. This Perspective aims to help researchers clarify the rational design of nanozymes in tumor therapy, offering a comprehensive guide in this emerging field.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Advanced Nanomaterials in Catalysis · Nanoplatforms for cancer theranostics · Nanocluster Synthesis and Applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Otolaryngology, Shenzhen Key Laboratory of Nanozymes and Translational Cancer Research, Shenzhen Institute of Translational Medicine, Shenzhen Second People’s Hospital, The First Affiliated Hospital of Shenzhen University, Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, National-Regional Key Technology Engineering Laboratory for Medical Ultrasound, School of Biomedical Engineering

Shenzhen University Medical School

Duke Kunshan University, No. 8 Duke Avenue, Kunshan, Jiangsu Province 215316, China

Funding

Science, Technology and Innovation Commission of Shenzhen Municipality · Shenzhen Portion of Shenzhen-Hong Kong Science and Technology Innovation Cooperation Zone

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