Control of Molecular Recognition via Modulation of the Nanoenvironment
Source abstract
Abstract
Many biological processes are driven by the interaction of a host with a guest molecule. We show such interactions can be modulated by carefully defining the local molecular environment to give a specific chemical outcome. Particularly, the selectivity of a host toward two different ions (Ca2+ and Al3+) is defined by it being in solution or the physisorbed state. In solution, the host displays greater selectivity toward Ca2+. When physisorbed, the selectivity profile of the host is reversed with enhanced binding of Al3+. This demonstrates a single host molecule can be tailored to selectively bind multiple guests by altering its nanoenvironment.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Molecular Sensors and Ion Detection · Supramolecular Chemistry and Complexes · Neuroscience and Neuropharmacology Research
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
The ARC Centre of Excellence for Nanoscale BioPhotonics, Institute for Photonics and Advanced Sensing, School of Physical Sciences, The University of Adelaide, Adelaide, South Australia 5005, Australia
Institute of High Performance Computing, 1 Fusionopolis Way, Singapore 138632, Singapore
City West Campus, University of South Australia, Adelaide, South Australia 5000, Australia
Funding
Australian Research Council
References (30)
Show source-provided references
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