journal article·2026-02-04

A Leaf-Adhesive, pH-Responsive Emamectin Benzoate Nanopesticide for Enhanced Efficacy and Reduced Toxicity

Ming Yang, Jie Wang, Bo Wang, Tengda Wang, Changcheng An, Yan Wang, Yilin Wang

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Abstract

A precise and low-toxicity pesticide delivery system is essential to enhancing pesticide efficacy and sustainability. Herein, a facile strategy is developed to construct leaf-adhesive and pH-responsive emamectin benzoate nanopesticides (EB NPs), in which Ca 2+ cross-links copolymer surfactant/nonionic surfactant/sodium alginate in coacervates. The uniform nanosize of EB NPs enables them to penetrate the microstructure of plant leaves, thereby improving their deposition and antiwashing ability. Moreover, the pH-responsive EB NPs facilitate precise release of encapsulated emamectin benzoate (EB) in the alkaline midgut (pH 9–10) of Plutella xylostella larvae by displacing Ca 2+ in the alginate nanoskeleton, along with the nanostructure disintegration. Notably, the acute toxicity of EB NPs to zebrafish is reduced to less than one-seventh that of commercial EB microemulsion formulation. This nanopesticide approach shows excellent potential to improve the pesticide efficacy and safety.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Polymer-Based Agricultural Enhancements · Pesticide and Herbicide Environmental Studies · Nanocomposite Films for Food Packaging

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

CAS Key Laboratory of Colloid, Interface, and Chemical Thermodynamics, Beijing National Laboratory for Molecular Sciences

Institute of Chemistry, Chinese Academy of Sciences

University of Chinese Academy of Sciences

University of Science and Technology of China

State Key Laboratory of Bioinspired Interfacial Materials Science, Suzhou Institute for Advanced Research, School of Nano Science and Technology

Institute of Environment and Sustainable Development in Agriculture

Chinese Academy of Agricultural Sciences

Funding

National Basic Research Program of China (973 Program) · Suzhou Key Laboratory of Bioinspired Interfacial Science · National Natural Science Foundation of China (NSFC)

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