Core (Polystyrene)–Shell [Poly(glycerol monomethacrylate)] Particles
Source abstract
Abstract
A set of water-swollen core-shell particles was synthesized by emulsion polymerization of a 1,3-dioxolane functional monomer in water. After removal of the 1,3-dioxolane group, the particles' shells were shown to swell in aqueous media. Upon hydrolysis, the particles increased in size from around 70 to 100-130 nm. A bicinchoninic acid assay and ζ-potential measurements were used to investigate the adsorption of lysozyme, albumin, or fibrinogen. Each of the core-shell particles adsorbed significantly less protein than the noncoated core (polystyrene) particles. Differences were observed as both the amount of difunctional, cross-linking monomer and the amount of shell monomer in the feed were changed. The core-shell particles were shown to be resistant to protein adsorption, and the degree to which the three proteins adsorbed was dependent on the formulation of the shell.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Advanced Polymer Synthesis and Characterization · Polymer Surface Interaction Studies · Hydrogels: synthesis, properties, applications
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Chemistry, University of Sheffield, Sheffield, South Yorkshire S3 7HF, U.K.
School of Chemistry and Biosciences, University of Bradford, Bradford, West Yorkshire BD7 1DP, U.K.
Department of Engineering, University of Bradford, Bradford, West Yorkshire BD7 1DP, U.K.
Funding
Engineering and Physical Sciences Research Council · Medical Research Council
References (69)
Show source-provided references
1. 10.1126/science.106327310.1126/science.1063273 ↗
2. 10.1053/j.gastro.2009.11.00310.1053/j.gastro.2009.11.003 ↗
3. 10.1002/macp.20090065710.1002/macp.200900657 ↗
4. 10.1007/s10856-010-4118-110.1007/s10856-010-4118-1 ↗
5. 10.1039/C3TB21208D10.1039/C3TB21208D ↗
6. 10.1016/j.cis.2013.12.00810.1016/j.cis.2013.12.008 ↗
7. 10.1163/15685620777999693110.1163/156856207779996931 ↗
8. 10.1016/0168-3659(87)90083-610.1016/0168-3659(87)90083-6 ↗
9. 10.1021/la902576610.1021/la9025766 ↗
10. 10.1002/anie.20030169410.1002/anie.200301694 ↗
11. 10.1021/bc200059v10.1021/bc200059v ↗
12. 10.1039/C4CC06075J10.1039/C4CC06075J ↗
13. 10.3390/s14071327310.3390/s140713273 ↗
14. 10.1039/c3ta15233b10.1039/c3ta15233b ↗
15. 10.1021/jp500516t10.1021/jp500516t ↗
16. 10.1016/j.bios.2014.10.05210.1016/j.bios.2014.10.052 ↗
17. 10.1021/bm400703d10.1021/bm400703d ↗
18. 10.1186/1477-3155-11-110.1186/1477-3155-11-1 ↗
19. 10.1002/app.3886410.1002/app.38864 ↗
20. Pelton R. · 2011 · 1
21. 10.1016/0032-3861(96)00253-410.1016/0032-3861(96)00253-4 ↗
22. 10.1039/b502628h10.1039/b502628h ↗
23. 10.1006/jcis.2001.755310.1006/jcis.2001.7553 ↗
24. 10.1021/ma035658m10.1021/ma035658m ↗
25. 10.1021/la020496t10.1021/la020496t ↗
26. 10.1021/la035302410.1021/la0353024 ↗
27. 10.1007/s00396005023210.1007/s003960050232 ↗
28. 10.1007/s00396005032910.1007/s003960050329 ↗
29. 10.1021/la980244l10.1021/la980244l ↗
30. 10.1021/la035478610.1021/la0354786 ↗
31. 10.1002/mabi.20100032410.1002/mabi.201000324 ↗
32. 10.1021/acsami.5b0142310.1021/acsami.5b01423 ↗
33. 10.1016/j.jconrel.2014.07.03710.1016/j.jconrel.2014.07.037 ↗
34. Moghimi S. M. · 2014 · 7710.1016/B978-0-12-408085-0.00006-6 ↗
35. 10.1016/j.exer.2013.07.01310.1016/j.exer.2013.07.013 ↗
36. 10.1016/S0142-9612(02)00081-910.1016/S0142-9612(02)00081-9 ↗
37. 10.1016/j.biomaterials.2006.09.02410.1016/j.biomaterials.2006.09.024 ↗
38. 10.1016/j.biomaterials.2007.08.02810.1016/j.biomaterials.2007.08.028 ↗
39. 10.1016/j.actbio.2014.02.04310.1016/j.actbio.2014.02.043 ↗
40. 10.1039/b813392a10.1039/b813392a ↗
41. 10.1016/j.biomaterials.2009.01.04110.1016/j.biomaterials.2009.01.041 ↗
42. 10.1039/c1sm05756a10.1039/c1sm05756a ↗
43. 10.1039/c3py00273j10.1039/c3py00273j ↗
44. 10.1021/bm900856r10.1021/bm900856r ↗
45. 10.1002/macp.1974.02175071110.1002/macp.1974.021750711 ↗
46. 10.1021/ma00079a00610.1021/ma00079a006 ↗
47. 10.1021/ma001623010.1021/ma0016230 ↗
48. 10.1002/pola.128710.1002/pola.1287 ↗
49. 10.1021/ma000781o10.1021/ma000781o ↗
50. 10.1002/mabi.20040021810.1002/mabi.200400218 ↗
51. 10.1021/ma902779910.1021/ma9027799 ↗
52. 10.1021/ma501140h10.1021/ma501140h ↗
53. 10.1021/ma300816m10.1021/ma300816m ↗
54. 10.1021/la901937p10.1021/la901937p ↗
55. 10.1021/ie701761410.1021/ie7017614 ↗
56. 10.1021/ma060794n10.1021/ma060794n ↗
57. 10.1016/j.eurpolymj.2006.01.00610.1016/j.eurpolymj.2006.01.006 ↗
58. 10.1021/la047046g10.1021/la047046g ↗
59. 10.1021/la402553710.1021/la4025537 ↗
60. 10.1016/j.ejps.2011.10.02510.1016/j.ejps.2011.10.025 ↗
61. 10.6028/jres.062.04110.6028/jres.062.041 ↗
62. 10.1016/S0006-3495(01)76266-210.1016/S0006-3495(01)76266-2 ↗
63. 10.1002/macp.1975.02176091210.1002/macp.1975.021760912 ↗
64. 10.1016/S0142-9612(99)00245-810.1016/S0142-9612(99)00245-8 ↗
65. 10.1098/rsif.2011.030810.1098/rsif.2011.0308 ↗
66. 10.2337/diacare.28.2.43710.2337/diacare.28.2.437 ↗
67. 10.1093/rheumatology/38.12.124910.1093/rheumatology/38.12.1249 ↗
68. 10.1136/bjo.70.4.24610.1136/bjo.70.4.246 ↗
69. 10.1093/qjmed/hcg12910.1093/qjmed/hcg129 ↗