Insulin Granule-Loaded MicroPlates for Modulating Blood Glucose Levels in Type-1 Diabetes
Source abstract
Abstract
(799.9 ± 134.83 vs 2234.60 ± 82.72 mg/dL) and increased insulin levels at 7 days post-implantation (1.14 ± 0.11 vs 0.38 ± 0.02 ng/mL), as compared to untreated diabetic mice. Collectively, these results demonstrate that INS-μPLs are a promising platform for the treatment of T1DM to be further optimized with the integration of smart glucose sensors.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Diabetes Management and Research · Pancreatic function and diabetes · Diabetes and associated disorders
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Laboratory of Nanotechnology for Precision Medicine, Fondazione Istituto Italiano di Tecnologia, Via Morego 30, Genoa 16163, Italy
Interventional Regenerative Medicine and Imaging Laboratory, Department of Radiology, Stanford University, Palo Alto, California 94304, United States
Unit of Endocrinology, Department of Internal Medicine & Medical Specialist (DIMI), University of Genoa, 16136 Genoa, Italy
Funding
National Institute of Diabetes and Digestive and Kidney Diseases · H2020 Marie Sk??odowska-Curie Actions
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