Matrix-Incorporated Polydopamine Layer as a Simple, Efficient, and Universal Coating for Laser Desorption/Ionization Time-of-Flight Mass Spectrometric Analysis
Source abstract
Abstract
Self-oxidative copolymerization of dopamine with α-cyano-4-hydroxycinnamic acid (CHCA) provides an efficient and multifunctional platform for laser desorption/ionization time-of-flight mass spectrometry (LDI-TOF-MS) analysis. The polydopamine coating layer embedded with the CHCA matrix can be readily formed on nanomaterials and solid substrates without additional surface treatments to generate an efficient LDI-TOF-MS platform for the analysis of small molecules as well as synthetic polymers. This coating can be further functionalized with specific ligands for target enrichment from complex biological media, providing analyte capture for subsequent LDI-TOF-MS analysis.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Mass Spectrometry Techniques and Applications · Analytical chemistry methods development · Analytical Chemistry and Sensors
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Carbon Composite Materials Research Center, Korea Institute of Science and Technology, 92 Chudong-ro, Bongdong-eup, Wanju-gun, Jeollabuk-do 55424, South Korea
Department of Chemistry, University of Massachusetts, Amherst, Massachusetts 01003, United States
Funding
Division of Chemistry · National Research Foundation of Korea · Korea Institute for Advancement of Technology · Korea Institute of Science and Technology
References (23)
Show source-provided references
1. 10.2174/138161205454693210.2174/1381612054546932 ↗
2. 10.1007/s00216-010-4138-110.1007/s00216-010-4138-1 ↗
3. 10.1021/acs.analchem.7b0059910.1021/acs.analchem.7b00599 ↗
4. 10.1021/ac102423210.1021/ac1024232 ↗
5. 10.1038/s41467-017-00220-410.1038/s41467-017-00220-4 ↗
6. 10.1007/s00216-017-0433-410.1007/s00216-017-0433-4 ↗
7. 10.1021/acsnano.7b0532810.1021/acsnano.7b05328 ↗
8. 10.1039/c6an00659k10.1039/c6an00659k ↗
9. 10.1039/c4cc10401c10.1039/c4cc10401c ↗
10. 10.1007/s13361-015-1223-x10.1007/s13361-015-1223-x ↗
11. 10.1021/ac020418a10.1021/ac020418a ↗
12. 10.1016/j.jasms.2009.04.00910.1016/j.jasms.2009.04.009 ↗
13. 10.1126/science.114724110.1126/science.1147241 ↗
14. 10.1088/0957-4484/22/49/49402010.1088/0957-4484/22/49/494020 ↗
15. 10.1021/am404104210.1021/am4041042 ↗
16. 10.1039/c7an00356k10.1039/c7an00356k ↗
17. 10.1021/am402414310.1021/am4024143 ↗
18. 10.1016/s0009-3084(01)00132-310.1016/s0009-3084(01)00132-3 ↗
19. 10.1002/(sici)1097-0231(199610)10:13<1575::aid-rcm658>3.0.co;2-c10.1002/(sici)1097-0231(199610)10:13<1575::aid-rcm658>3.0.co;2-c ↗
20. 10.1021/am300054z10.1021/am300054z ↗
21. 10.1002/chem.20140406710.1002/chem.201404067 ↗
22. 10.1016/j.biomaterials.2012.06.06710.1016/j.biomaterials.2012.06.067 ↗
23. 10.1039/c4ra05255b10.1039/c4ra05255b ↗