Fabrication of Macroporous Polymeric Membranes through Binary Convective Deposition

Binary convective deposition of silica/polystyrene under a number of different operating conditions is used to form nanoporous polymeric membranes with uniform and repeatable pore size throughout and across the membrane. One micrometer silica microspheres and 100 nm PS nanoparticles are codeposited from suspension under conditions where respective constituent fluxes are matched. Membrane thickness is controlled through single and consecutive monolayer and multilayer depositions. Consecutive monolayer depositions result in thin films with highest order and packing. Polymeric membranes were successfully fabricated from a continuous thin film by etching the SiO(2) microspheres with HF or KOH. Etching proceeds radially inward from the polymer-oxide interface suggesting that etchant/thin film interfacial energies help create the initial etching profile and drastically increase the overall etching rate. These membranes, of tunable pore size and functionality, will be ideal for targeted bioseparations specifically in the partition of pathogen particles out of blood suspensions.