A Facile Strategy toward Conjugated Polyelectrolyte with Oligopeptide as Pendants for Biological Applications
Source abstract
Abstract
We report a facile yet efficient strategy to synthesize biofunctionalized conjugated polyelectrolyte using click reaction between an amphiphilic oligopeptide (R10) and organic soluble polyfluorene (PF) as an example. PF-R10 shows the absorption and emission maxima at ~380 and ~430 nm in water, respectively. In addition, it exhibits enhanced fluorescence in acidic circumstance as compared to that in neutral environment because of reduced aggregation, which is confirmed by laser light scattering and atomic force microscopy studies. In view of the penetration property of the grafted R10 peptide, PF-R10 shows excellent cell uptake and labeling ability in cellular imaging.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Luminescence and Fluorescent Materials · Advanced biosensing and bioanalysis techniques · Dendrimers and Hyperbranched Polymers
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Chemical and Biomolecular Engineering, National University of Singapore, 4 Engineering Drive 4, Singapore 117576, Singapore
References (33)
Show source-provided references
1. Pinto M. R. · Synthesis · 2002 · 1293
2. Huang F. · J. Am. Chem. Soc. · 2004 · 126 · 984510.1021/ja0476765 ↗
3. Seo J. H. · J. Am. Chem. Soc. · 2009 · 131 · 1822010.1021/ja908441c ↗
4. Thomas S. W. · Chem. Rev. · 2007 · 107 · 133910.1021/cr0501339 ↗
5. Feng X. · Chem. Soc. Rev. · 2010 · 39 · 241110.1039/b909065g ↗
6. Pu K. · Adv. Funct. Mater. · 2011 · 21 · 340810.1002/adfm.201101153 ↗
7. Zhu C. · Chem. Rev. · 2012 · 112 · 468710.1021/cr200263w ↗
8. Kim I. B. · Bioconjugate Chem. · 2007 · 18 · 81510.1021/bc0603440 ↗
9. Pu K. · Chem. Mater. · 2009 · 21 · 381610.1021/cm901197s ↗
10. Pu K. · Adv. Funct. Mater. · 2010 · 20 · 277010.1002/adfm.201000495 ↗
11. Pu K. · Chem. Mater. · 2010 · 22 · 673610.1021/cm102788b ↗
12. McRae R. L. · J. Am. Chem. Soc. · 2008 · 130 · 785110.1021/ja8007402 ↗
13. Li K. · Chem. Mater. · 2011 · 23 · 211310.1021/cm103557h ↗
14. Ding D. · Nanoscale · 2011 · 3 · 199710.1039/c0nr00950d ↗
15. Pu, K. Y.; Wang, G.; Liu, B.InConjugated Polyelectrolytes: Fundamentals and Applications;Liu, B.; Bazan, G. C., Eds.Wiley-VCH:Germany, 2013; pp1–64.10.1002/9783527655700.ch1 ↗
16. Chaturvedi V. · Macromolecules · 1993 · 26 · 260710.1021/ma00062a032 ↗
17. Brodowski G. · Macromolecules · 1996 · 29 · 696210.1021/ma960256i ↗
18. Balanda P. B. · Macromolecules · 1999 · 32 · 397010.1021/ma982017w ↗
19. Jiang H. · Angew. Chem., Int. Ed. · 2009 · 48 · 430010.1002/anie.200805456 ↗
20. Child A. D. · Macromolecules · 1994 · 27 · 197510.1021/ma00085a050 ↗
21. Faïd K. · Chem. Commun. · 1996 · 276110.1039/CC9960002761 ↗
22. Burrows H. D. · Macromolecules · 2004 · 37 · 742510.1021/ma048780+ ↗
23. Phillips R. L. · J. Am. Chem. Soc. · 2008 · 130 · 695210.1021/ja802094s ↗
24. Liu J. · Polym. Chem. · 2012 · 3 · 156710.1039/c2py20113e ↗
25. Pu K. · Biomacromolecules · 2011 · 12 · 296610.1021/bm200563a ↗
26. Fruth A. · Macromolecules · 2010 · 43 · 46710.1021/ma901020v ↗
27. Kolb H. C. · Angew. Chem., Int. Ed. · 2001 · 40 · 200410.1002/1521-3773(20010601)40:11<2004::AID-ANIE2004>3.0.CO;2-5 ↗
28. Stanley L. M. · Chem. Rev. · 2008 · 108 · 288710.1021/cr078371m ↗
29. Wang H. · Macromol. Rapid Commun. · 2007 · 28 · 164510.1002/marc.200700221 ↗
30. Demas J. N. · J. Phys. Chem. · 1971 · 75 · 99110.1021/j100678a001 ↗
31. Lee S. H. · Macromolecules · 2011 · 44 · 474210.1021/ma200574d ↗
32. Qin C. · J. Mater. Chem. · 2010 · 20 · 795710.1039/c0jm01094d ↗
33. Futaki S. · J. Biol. Chem. · 2001 · 276 · 583610.1074/jbc.M007540200 ↗