journal article·2025-01-08

Reversible Lubricating Layer for Improving the Endoscope Field with High Transparency and Antipollution Property

Jinbo Liu, Qiannan Wang, Fuhao Shen, Congcong Zhang, Chang Cheng, Haitao Deng, Enfeng Yang, Xiao Chen, Kefan Fang, Yuan Zhou, Yuan Su, Jing Zhang, Dianyu Wang

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Abstract

Endoscopes, a minimally invasive medical tool, are susceptible to impaired visibility due to the adhesion of biological fluids. However, traditional self-cleaning coatings face limitations in terms of transparency and sustainability, making it difficult to apply them to lenses. Inspired by the phospholipid layer of the eye, a reversible lubricating layer (RL-layer) with low-adhesion and high-transparency properties is reported. Even coagulated blood can be easily removed due to the low surface tension and easy swing of the brushes. In addition, the silicon-oxygen bonds can be cleaved by fluoride ions, thereby achieving reversible modification and showing potential in sustainable usage. To prove the concept, biomimetic endoscopic lenses are employed in vivo experiments. The results indicate that it consistently maintains a clear vision in narrow spaces containing mucus and exhibits excellent biocompatibility. The reversible lubricating layer provides valuable reference significance for self-cleaning coatings in other fields.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Surface Modification and Superhydrophobicity · Ocular Surface and Contact Lens · Advanced Sensor and Energy Harvesting Materials

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

School of Chemical Engineering, Zhengzhou University, Zhengzhou 450001, China

College of Stomatology, Xi’an Jiaotong University, Xi’an 710049, China

Key Laboratory of Bioinspired Smart Interfacial Science, Technical Institute of Physics and Chemistry Chinese Academy of Sciences, Beijing 100190, P. R. China

Biomedical Pioneering Innovation Center (BIOPIC), School of Life Sciences, Peking University, Beijing, 100871 China

Advanced Medical Technology Center, The First Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China

Funding

China Postdoctoral Science Foundation · National Natural Science Foundation of China · Key Laboratory of Bio-inspired Materials and Interfacial Science, Chinese Academy of Sciences

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