Efficient Purification of 2,6-Lutidine by Nonporous Adaptive Crystals of Pillararenes
Source abstract
Abstract
2,6-Lutidine (2,6-LT) is a very important raw material in the chemical industry, but the impurities of 3-picoline (3-PC) and 4-picoline (4-PC) existing in 2,6-LT seriously affect its quality. Considering different molecular sizes of these three compounds, herein, we exploit nonporous adaptive crystals (NACs) of pillararenes as purifying agents for removal of 3-PC and 4-PC in 2,6-LT. We find that per-ethylated pillar[5]arene (EtP5) can selectively adsorb 3-PC and 4-PC, while negligible capture of 2,6-LT is observed, resulting in improvement of the purity of 2,6-LT up to 94.9%. Single-crystal structures indicate that the excellent selectivity originates from the size match and complexation stability differences among different host/guest pairs. After purification, NACs of EtP5 can be easily regenerated and used in the next run without a significant performance degradation.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Supramolecular Chemistry and Complexes · Crystallography and molecular interactions · Metal-Organic Frameworks: Synthesis and Applications
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Stoddart Institute of Molecular Science, Department of Chemistry, Zhejiang University, Hangzhou 310027, P. R. China
ZJU-Hangzhou Global Scientific and Technological Innovation Center, Hangzhou 311215, P. R. China
Green Catalysis Center and College of Chemistry, Zhengzhou University, Zhengzhou 450001, P. R. China
Funding
Ministry of Science and Technology of the People's Republic of China · King Abdullah University of Science and Technology · National Natural Science Foundation of China · Natural Science Foundation of Zhejiang Province · Starry Night Science Fund of Zhejiang University Shanghai Institute for Advanced Study
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