Temperature-Dependent Coherent Tunneling across Graphene–Ferritin Biomolecular Junctions

Nipun Kumar Gupta; Senthil Kumar Karuppannan; Rupali Reddy Pasula; Ayelet Vilan; Jens Martin; Wentao Xu; Esther Maria May; Andrew R. Pike; Hippolyte P. A. G. Astier; Teddy Salim; Sierin Lim; Christian A. Nijhuis

doi:10.1021/acsami.2c11263

journal article·2022-10-05Open access

Temperature-Dependent Coherent Tunneling across Graphene–Ferritin Biomolecular Junctions

Nipun Kumar Gupta, Senthil Kumar Karuppannan, Rupali Reddy Pasula, Ayelet Vilan, Jens Martin, Wentao Xu, Esther Maria May, Andrew R. Pike, Hippolyte P. A. G. Astier, Teddy Salim, Sierin Lim, Christian A. Nijhuis

ACS Applied Materials & Interfaces· Volume 14· Issue 39

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Source abstract

Abstract

Understanding the mechanisms of charge transport (CT) across biomolecules in solid-state devices is imperative to realize biomolecular electronic devices in a predictive manner. Although it is well-accepted that biomolecule-electrode interactions play an essential role, it is often overlooked. This paper reveals the prominent role of graphene interfaces with Fe-storing proteins in the net CT across their tunnel junctions. Here, ferritin (AfFtn-AA) is adsorbed on the graphene by noncovalent amine-graphene interactions confirmed with Raman spectroscopy. In contrast to junctions with metal electrodes, graphene has a vanishing density of states toward its intrinsic Fermi level ("Dirac point"), which increases away from the Fermi level. Therefore, the amount of charge carriers is highly sensitive to temperature and electrostatic charging (induced doping), as deduced from a detailed analysis of CT as a function of temperature and iron loading. Remarkably, the temperature dependence can be fully explained within the coherent tunneling regime due to excitation of hot carriers. Graphene is not only demonstrated as an alternative platform to study CT across biomolecular tunnel junctions, but it also opens rich possibilities in employing interface electrostatics in tuning CT behavior.

Source: openalex_inverted_index · Quality: baseline

Research context

Nanomaterials

OpenAlex topics: Graphene research and applications · Molecular Junctions and Nanostructures · Electrochemical sensors and biosensors

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Singapore

Centre for Advanced 2D Materials, National University of Singapore, 6 Science Drive 2, Singapore 117546, Singapore

School of Chemical and Biomedical Engineering, Nanyang Technological University, 70 Nanyang Drive, Singapore 637457, Singapore

Department of Chemical and Biological Physics, Weizmann Institute of Science, Rehovot 76100, Israel

Chemistry-School of Natural and Environmental Sciences, Newcastle University, Newcastle upon Tyne NE1 7RU, U.K.

School of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798, Singapore

Hybrid Materials for Opto-Electronics Group, Department of Molecules and Materials, MESA+ Institute for Nanotechnology and Centre for Brain-Inspired Nano Systems, Faculty of Science and Technology, University of Twente, P.O. Box 217, 7500 AE Enschede, The Netherlands

Funding

Ministry of Education - Singapore · National Research Foundation Singapore

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