journal article·2022-09-21Open access

Reversible Self-Assembled Monolayers with Tunable Surface Dynamics for Controlling Cell Adhesion Behavior

Sing Yee Yeung, Yulia Sergeeva, Guoqing Pan, Silvia Mittler, Thomas Ederth, Tommy Dam, Peter Jönsson, Zahra El-Schich, Anette Gjörloff Wingren, Adam Tillo, Sabrina Hsiung Mattisson, Bo Holmqvist, Maria M. Stollenwerk, Börje Sellergren

ACS Applied Materials & Interfaces· Volume 14· Issue 37

Abstract

- and ω-(GRGDS)-, α-benzamidino bolaamphiphiles. Cell shape and morphology were influenced by the strength of the interactions between the amidine-functionalized amphiphiles and the oxoacid of the underlying SAMs. Dynamic control over surface composition, achieved by the addition of inert filler amphiphiles to the RGD-functionalized rSAMs, reversed the cell adhesion process. In summary, rSAMs featuring mobile bioactive ligands offer unique capabilities to influence and control cell adhesion behavior, suggesting a broad use in biomaterial design, tissue engineering, and regenerative medicine.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Polymer Surface Interaction Studies · Molecular Junctions and Nanostructures · Supramolecular Self-Assembly in Materials

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Biomedical Sciences and Biofilms-Research Center for Biointerfaces (BRCB), Faculty of Health and Society, Malmö University, 205 06 Malmö, Sweden

Institute for Advanced Materials, School of Materials Science and Engineering, Jiangsu University, Zhenjiang, Jiangsu 212 013, China

Department of Physics and Astronomy, University of Western Ontario, 1151 Richmond Street, London, Ontario, Canada N6A 3K7

Division of Biophysics and Bioengineering, Department of Physics, Chemistry and Biology (IFM), Linköping University, 581 83 Linköping, Sweden

Division of Physical Chemistry, Department of Chemistry, Lund University, 221 00 Lund, Sweden

ImaGene-iT AB, Medicon Village, Scheelevägen 2, 223 81 Lund, Sweden

Funding

Vetenskapsr?det · H2020 Marie Sklodowska-Curie Actions · H2020 European Research Council

References (51)

Show source-provided references
1. 10.1146/annurev.cellbio.12.1.46310.1146/annurev.cellbio.12.1.463 ↗
2. 10.1038/nature0962110.1038/nature09621 ↗
3. 10.1038/ncb259210.1038/ncb2592 ↗
4. 10.1126/science.111699510.1126/science.1116995 ↗
5. 10.1016/j.cell.2006.06.04410.1016/j.cell.2006.06.044 ↗
6. 10.1016/j.tibtech.2018.01.00810.1016/j.tibtech.2018.01.008 ↗
7. 10.1038/nchem.109010.1038/nchem.1090 ↗
8. 10.1039/C8CS00053K10.1039/C8CS00053K ↗
9. 10.1186/s42833-019-0007-110.1186/s42833-019-0007-1 ↗
10. 10.1038/s41570-018-012010.1038/s41570-018-0120 ↗
11. 10.3389/fmats.2019.0003910.3389/fmats.2019.00039 ↗
12. 10.1002/anie.20180900610.1002/anie.201809006 ↗
13. 10.1016/j.chempr.2017.11.00610.1016/j.chempr.2017.11.006 ↗
14. 10.1038/nmat447410.1038/nmat4474 ↗
15. 10.1038/nnano.2013.20510.1038/nnano.2013.205 ↗
16. 10.1002/anie.20090113010.1002/anie.200901130 ↗
17. 10.1039/C4CC06649A10.1039/C4CC06649A ↗
18. 10.1002/anie.20211310310.1002/anie.202113103 ↗
19. 10.1002/anie.20130627810.1002/anie.201306278 ↗
20. 10.1073/pnas.211722111910.1073/pnas.2117221119 ↗
21. 10.1039/C4CS00034J10.1039/C4CS00034J ↗
22. 10.1021/ja501664f10.1021/ja501664f ↗
23. 10.1126/science.abh360210.1126/science.abh3602 ↗
24. 10.1039/a705397e10.1039/a705397e ↗
25. 10.1039/B906608J10.1039/B906608J ↗
26. 10.1021/acs.nanolett.1c0050110.1021/acs.nanolett.1c00501 ↗
27. 10.1002/anie.20120565110.1002/anie.201205651 ↗
28. 10.1002/1521-3773(20010316)40:6<1093::AID-ANIE10930>3.0.CO;2-Q10.1002/1521-3773(20010316)40:6<1093::AID-ANIE10930>3.0.CO;2-Q ↗
29. 10.1172/JCI1260910.1172/JCI12609 ↗
30. 10.1073/pnas.171065311510.1073/pnas.1710653115 ↗
31. 10.1002/adhm.20160086210.1002/adhm.201600862 ↗
32. 10.1016/j.bbamem.2017.05.00510.1016/j.bbamem.2017.05.005 ↗
33. 10.1002/adhm.20150039810.1002/adhm.201500398 ↗
34. 10.1021/acscentsci.7b0041210.1021/acscentsci.7b00412 ↗
35. 10.1002/chem.20030547710.1002/chem.200305477 ↗
36. 10.1039/a905193g10.1039/a905193g ↗
37. 10.1021/ac950835610.1021/ac9508356 ↗
38. 10.1021/acs.langmuir.8b0022610.1021/acs.langmuir.8b00226 ↗
39. 10.1021/acs.langmuir.9b0145210.1021/acs.langmuir.9b01452 ↗
40. 10.1039/b801646a10.1039/b801646a ↗
41. 10.1039/c3cs60198f10.1039/c3cs60198f ↗
42. 10.1016/S0142-9612(00)00259-310.1016/S0142-9612(00)00259-3 ↗
43. 10.1080/08927014.2011.62547410.1080/08927014.2011.625474 ↗
44. 10.1083/jcb.100.6.194810.1083/jcb.100.6.1948 ↗
45. 10.1016/S0006-3495(93)81277-310.1016/S0006-3495(93)81277-3 ↗
46. Connors K. A. · 1987
47. 10.1021/la049247q10.1021/la049247q ↗
48. 10.1246/cl.1998.66910.1246/cl.1998.669 ↗
49. Pollard J. W. · 1997 · 7510.1385/0896034410 ↗
50. Northrope J. H. · 1939
51. 10.1002/anie.20170863510.1002/anie.201708635 ↗