Protein Nanocage-Based Photo-Controlled Nitric Oxide Releasing Platform

Xiao Li; Yajie Zhang; Jian Sun; Weijian Chen; Xuewei Wang; Fenli Shao; Yuyu Zhu; Fude Feng; Yang Sun

doi:10.1021/acsami.7b03962

journal article·2017-06-14

Protein Nanocage-Based Photo-Controlled Nitric Oxide Releasing Platform

Xiao Li, Yajie Zhang, Jian Sun, Weijian Chen, Xuewei Wang, Fenli Shao, Yuyu Zhu, Fude Feng, Yang Sun

ACS Applied Materials & Interfaces· Volume 9· Issue 23

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Source abstract

Abstract

A photoactive NO releasing system was constructed by incorporation of NO-bound Fe-S clusters into horse spleen apoferritin cavities with high loading efficacy. The composites retained intact core-shell structure and indicated advantages such as enhanced stability, reduced cytotoxicity, efficient cellular uptake, and photocontrolled NO releasing property.

Source: openalex_inverted_index · Quality: baseline

Research context

Nanomaterials Composites

OpenAlex topics: Nitric Oxide and Endothelin Effects · Nanoplatforms for cancer theranostics · Sulfur Compounds in Biology

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Polymer Science & Engineering, School of Chemistry & Chemical Engineering, and ‡State Key Laboratory of Pharmaceutical Biotechnology and Collaborative Innovation Center of Chemistry for Life Sciences, School of Life Sciences, Nanjing University, Nanjing 210023, P. R. China

Funding

Ministry of Education of the People's Republic of China · Ministry of Science and Technology of the People's Republic of China · Nanjing University · National Natural Science Foundation of China · Collaborative Innovation Center of Chemistry for Life Sciences, Nanjing University · Central People's Government of the People's Republic of China

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