Thermo-sensitive poly( l -methionine) hydrogel facilitates regenerative repair of diabetic wounds by modulating immune microenvironments
Source abstract
Abstract
Achieving complete skin regeneration remains challenging in clinical practice. To address this issue, an injectable, thermo-sensitive hydrogel of poly(ethylene glycol)-block-poly(L-methionine) (EG45Met25) is developed. EG45Met25 promotes chronic wound repair and appendage regeneration through synergistic antioxidant and anti-inflammatory effect mechanisms, representing a promising strategy for clinical regenerative therapies.
Source: europepmc · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Wound Healing and Treatments · Tissue Engineering and Regenerative Medicine · Hydrogels: synthesis, properties, applications
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
State Key Laboratory of Polymer Science and Technology, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun 130022, P. R. China
School of Applied Chemistry and Engineering, University of Science and Technology of China, 96 Jinzhai Road, Hefei 230026, P. R. China
Funding
National Natural Science Foundation of China · Department of Science and Technology of Jilin Province · Youth Innovation Promotion Association of the Chinese Academy of Sciences
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