Microfluidic Crystallization of Surfactant-Free Doped Zinc Sulfide Nanoparticles for Optical Bioimaging Applications
Source abstract
Abstract
The room-temperature controlled crystallization of monodispersed ZnS nanoparticles (average size of 5 nm) doped with luminescent ions (such as Mn2+, Eu3+, Sm3+, Nd3+, and Yb3+) was achieved via a microfluidic approach. The preparation did not require any stabilizing ligands or surfactants, minimizing potential sources of impurities. The synthesized nanomaterials were characterized from a structural (XRD and XAS at lanthanide L3 edges), morphological (TEM), and compositional (XPS, ICP-MS) perspective, giving complementary information on the materials' features. In view of potential applications in the field of optical bioimaging, the optical emission properties of the doped nanoparticles were assessed, and samples showed strong luminescent properties while being less affected by self-quenching mechanisms. Furthermore, in vitro cytotoxicity experiments were conducted, showing no negative effects and evidencing the appeal of the synthesized materials for potential applications in the field of optical bioimaging.
Source: europepmc · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Quantum Dots Synthesis And Properties · Gold and Silver Nanoparticles Synthesis and Applications · Biosensors and Analytical Detection
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Dipartimento di Scienze Chimiche, Università degli Studi di Padova, Via Marzolo 1, 35131 Padova, Italy
INSTM, UdR di Padova, Via Marzolo 1, 35131 Padova, Italy
Dipartimento di Biologia, Università degli Studi di Padova, Via Bassi 58B, 35131 Padova, Italy
Karlsruher Institut für Technologie (KIT), Institut für Technische Chemie und Polymerchemie (ITCP), Engesserstr. 20, 76131 Karlsruhe, Germany
NRG, Dipartimento di Biotecnologie, Università di Verona and INSTM, RU Verona, Strada Le Grazie 15, 37314 Verona, Italy
Karlsruher Institut für Technologie (KIT), Institut für Nanotechnologie (INT) & Karlsruhe Nano Micro Facility (KNMF), Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen, Germany
Department of Materials and Earth Sciences, Technical University Darmstadt, Alarich-Weiss-Str. 2, 64287 Darmstadt, Germany
Funding
Universit? degli Studi di Verona · China Scholarship Council
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