journal article·2022-08-03

Natural Soybean Milk-Derived Bioactive Coatings for Enhanced Wound Healing

Peikun Xin, Shuyan Han, Jun Huang, Xinru You, Jun Wu

ACS Applied Materials & Interfaces· Volume 14· Issue 30
Publisher page

Abstract

Foodborne biomaterials, derived from diets, comprise selfassembled collections of many micro- or nanoscale units with abundant nutrients and active substances. In this study, soybean milk (SBM) was selected as a tissue engineering product for simple and feasible wound repair. SBM is a common drink prepared from soybeans and is rich in soy protein, soy isoflavones, and other bioactive components. Thus, SBM has substantial potential for antioxidation and tissue remodeling. Here, the multifunctional effect of SBM as a bioactive coating for promoting wound healing was studied. The results showed that SBM has good biocompatibility and biological activity. It efficiently scavenges intracellular reactive oxygen species, significantly enhances epithelial cell migration, and improves angiogenesis, thereby accelerating tissue remodeling. The results of animal experiments further confirmed that the SBM-bioinspired coating has promising applications for cutaneous wound regeneration.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Wound Healing and Treatments · Electrospun Nanofibers in Biomedical Applications · Silk-based biomaterials and applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

School of Biomedical Engineering, State Key Laboratory of Oncology in South China, Sun Yat-Sen University, Guangzhou 510006, China

Institute of Biological and Medical Engineering, Guangdong Academy of Sciences, Guangzhou 510316, China

Department of Pediatrics, The Seventh Affiliated Hospital, Sun Yat-Sen University, Shenzhen 518107, China

RNA Biomedical Institute, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510120, China

Funding

Guangdong Province Introduction of Innovative R&D Team · Shenzhen Fundamental Research Program · National Natural Science Foundation of China

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