Construction of pH-Sensitive “Submarine” Based on Gold Nanoparticles with Double Insurance for Intracellular pH Mapping, Quantifying of Whole Cells and in Vivo Applications
Source abstract
Abstract
A series of "submarines", which composed of gold nanoparticles and modified with rhodamine and fluorescein derivatives, were presented. With dual sensitive units for both acidic and basic environment, these "gold nano-submarines" not only allow efficient intracellular pH mapping but also provide more accurate quantitative detection of pH alteration under different stimuli with distinct pH quantification range. Moreover, they even have the ability to pass through the blood brain barrier (BBB).
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Advanced biosensing and bioanalysis techniques · Molecular Sensors and Ion Detection · Advanced Nanomaterials in Catalysis
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Key Laboratory of Green Chemistry and Technology (Ministry of Education), College of Chemistry, Sichuan University, Chengdu 610064, China
Funding
Ministry of Science and Technology of the People's Republic of China · National Natural Science Foundation of China
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