DataVXACS Applied Materials & InterfacesPaper
journal article·2022-08-31Open access

Covalent Organic Framework Based on Azacalix[4]arene for the Efficient Capture of Dialysis Waste Products

Tina Skorjanc, Dinesh Shetty, Felipe Gándara, Simon Pascal, Nawavi Naleem, Salma Abubakar, Liaqat Ali, Abdul Khayum Mohammed, Jesus Raya, Serdal Kirmizialtin, Olivier Siri, Ali Trabolsi

ACS Applied Materials & Interfaces· Volume 14· Issue 34
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Source abstract

Abstract

Azacalix[n]arenes (ACAs) are lesser-known cousins of calix[n]arenes that contain amine bridges instead of methylene bridges, so they generally have higher flexibility due to enlarged cavities. Herein, we report a highly substituted cationic azacalix[4]arene-based covalent organic framework (ACA-COF) synthesized by the Zincke reaction under microwave irradiation. The current work is a rare example of a synthetic strategy that utilizes the chemical functionalization of an organic macrocycle to constrain its conformational flexibility and, thereby, produce an ordered material. Considering the ACA cavity dimensions, and the density and diversity of the polar groups in ACA-COF, we used it for adsorption of uric acid and creatinine, two major waste products generated during hemodialysis treatment in patients with renal failure. This type of application, which has the potential to save ∼400 L of water per patient per week, has only been recognized in the last decade, but could effectively address the problem of water scarcity in arid areas of the world. Rapid adsorption rates (up to k = 2191 g mg–1 min–1) were observed in our COF, exceeding reported values by several orders of magnitude.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Covalent Organic Framework Applications · Metal-Organic Frameworks: Synthesis and Applications · Luminescence and Fluorescent Materials

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Science Division, New York University Abu Dhabi, Saadiyat Island, 129188 Abu Dhabi, UAE

Materials Research Laboratory, University of Nova Gorica, Vipavska 11c, 5270 Ajdovscina, Slovenia

Department of Chemistry & Center for Catalysis and Separations (CeCaS), Khalifa University of Science and Technology, 127788 Abu Dhabi, UAE

Instituto de Ciencia de Materiales de Madrid-CSIC, C. Sor Juana Inés de la Cruz 3, 28049 Madrid, Spain

Centre Interdisciplinaire de Nanosciences de Marseille (CINaM), Aix Marseille Univ, CNRS, UMR 7325, Campus de Luminy, 13288 Marseille, France

Membrane Biophysics and NMR, Institute of Chemistry, University of Strasbourg, CNRS, Rue Blaise Pascal 1, 67081 Strasbourg, France

NYUAD Water Research Center, New York University Abu Dhabi (NYUAD), Saadiyat Island, 129188 Abu Dhabi, UAE

Funding

Khalifa University of Science, Technology and Research · Tamkeen · H2020 Spreading Excellence and Widening Participation · New York University Abu Dhabi

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