journal article·2017-03-22

Collagen-Based Photoactive Agent for Tissue Bonding

Justina Pupkaite, Manuel Ahumada, Sarah Mclaughlin, Maha Temkit, Sura Alaziz, Richard Seymour, Marc Ruel, Irene Kochevar, May Griffith, Erik J. Suuronen, Emilio I. Alarcon

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Abstract

Using a combination of methacrylated collagen and the photosensitizer rose Bengal, a new light-activated biomimetic material for tissue sutureless bonding was developed. This formulation was cross-linked using green light. In vivo tests in mice demonstrate the suitability of the material for sutureless wound closure.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Laser Applications in Dentistry and Medicine · Surgical Sutures and Adhesives · Photopolymerization techniques and applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Division of Cardiac Surgery, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, Canada

Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden

Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, United States

Department of Biochemistry, Microbiology, and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Canada

Funding

AFA F?rs?kring · Natural Sciences and Engineering Research Council of Canada · University of Ottawa Heart Institute

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