Self-Doped Rutile Titania with High Performance for Direct and Ultrafast Assay of H₂O₂

Detection of H2O2 is important for the applications in environmental protection, pharmaceutical industries, food production, and clinical control. Current colorimetric assay of H2O2 based on enzyme or nanomaterials always needs TMB or other peroxidase substrate as coloration species. Furthermore, the corresponding response time including incubation process is in order of minute. In this study, we report on the synthesis of heavily Ti(3+)-doped TiO2 composed of spherelike nanoparticles by pulsed laser ablation method. This TiO2 can directly detect H2O2 without using TMB or any other peroxidase substrate and is free from incubation process. In addition, the detection sensitivity is compatible with or better than that of the natural enzyme or other nanomaterials. Hence, the self-doped TiO2 nanoparticles provide a novel, direct, ultrafast approach for H2O2 assay application.