Single-Layered Graphene/Au-Nanoparticles-Based Love Wave Biosensor for Highly Sensitive and Specific Detection of Staphylococcus aureus Gene Sequences
Source abstract
Abstract
In this work, a single-layered graphene (SLG)/Au-nanoparticles (NPs)-based Love wave biosensor was prepared for detection of Staphylococcus aureus (S. aureus) gene sequences. The annealing process was proposed to obtain a larger-area interface with ssDNA. The sensitivity was verified by detecting S. aureus gene sequences with a linear detection ranging from 0 to 10 nmol/L, where the limit of detection (LOD) was only 12.4 pg/mL. The stable state of the biosensors based on SLG/Au NPs in the liquid phase could be kept for more than 0.5 h (±0.1°), and the specificity was verified by detecting noncomplementary ssDNA and one- and three-base mismatched ssDNA. The results of our study suggest that a Love wave biosensor based on SLG/Au NPs hold great potential in clinical testing and diagnosis.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Acoustic Wave Resonator Technologies · Advanced biosensing and bioanalysis techniques · Mechanical and Optical Resonators
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Key Laboratory of Optoelectronic Technology & Systems, Ministry of Education, International R & D Center of Micro-nano Systems and New Materials Technology, College of Optoelectronic Engineering, Chongqing University, Chongqing 400044, China
School of Chemistry and Chemical Engineering, Chongqing University, Chongqing 400030, China
Funding
Ministry of Education of the People's Republic of China · Ministry of Science and Technology of the People's Republic of China · National Natural Science Foundation of China · Chongqing Municipality
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