journal article·2014-03-12

Water-Soluble Triscyclometalated Organoiridium Complex: Phosphorescent Nanoparticle Formation, Nonlinear Optics, and Application for Cell Imaging

Yuanpeng Fan, Jingyi Zhao, Qifan Yan, Peng R. Chen, Dahui Zhao

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Abstract

Two water-soluble triscyclometalated organoiridium complexes, 1 and 2, with polar side chains that form nanoparticles emitting bright-red phosphorescence in water were synthesized. The optimal emitting properties are related to both the triscyclometalated structure and nanoparticle-forming ability in aqueous solution. Nonlinear optical properties are also observed with the nanoparticles. Because of their proper cellular uptake in addition to high emission brightness and effective two-photon absorbing ability, cell imaging can be achieved with nanoparticles of 2 bearing quaternary ammonium side chains at ultra-low effective concentrations using NIR incident light via the multiphoton excitation phosphorescence process.
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Research context

OpenAlex topics: Luminescence and Fluorescent Materials · Nonlinear Optical Materials Studies · Nanoplatforms for cancer theranostics

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Beijing National Laboratory for Molecular Sciences, Department of Applied Chemistry and the Key Laboratory of Polymer Chemistry and Physics of the Ministry of Education, College of Chemistry, Peking University, Beijing 100871, China

Beijing National Laboratory for Molecular Sciences, Synthetic and Functional Biomolecules Center, Department of Chemical Biology, Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China

Laboratory of Chemical Genomics, School of Chemical Biology and Biotechnology, Shenzhen Graduate School of Peking University, Shenzhen 518055, China

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