Functional Mesoporous Silica Nanoparticles for the Selective Sequestration of Free Fatty Acids from Microalgal Oil

A series of 2d-hexagonally packed mesoporous silica nanoparticle material with 10 nm pore diameter (MSN-10) covalently functionalized with organic surface modifiers have been synthesized via a post-synthesis grafting method. The material structure has been characterized by powder X-ray diffraction, electron microscopy, and nitrogen sorption analyses, and the free fatty acid (FFA) sequestration capacity and selectivity was investigated and quantified by thermogravimetric and GC/MS analysis. We discovered that aminopropyl functionalized 10 nm pore mesoporous silica nanoparticle material (AP-MSN-10) sequestered all available FFAs and left nearly all other molecules in solution from a simulated microalgal extract containing FFAs, sterols, terpenes, and triacylglycerides. We also demonstrated selective FFA sequestration from commercially available microalgal oil.