journal article·2015-03-11

Bifunctional Magnetic-Fluorescent Nanoparticles: Synthesis, Characterization, and Cell Imaging

Yanjiao Lu, Yang Zheng, Shusen You, Feng Wang, Zhuo Gao, Jie Shen, Wantai Yang, Meizhen Yin

Publisher page

Abstract

A new type of bifunctional magnetic-fluorescent Fe3O4@SiO2-PDI-PAA/Ca(2+) nanoparticles has been prepared by coating PDI-cored star polymers (PDI-PAA) onto the surface of Fe3O4@SiO2 core-shell nanostructures. The morphology and properties of the composite nanoparticles are investigated by transmission electron microscopy, ultraviolet-visible spectrometry, fluorescence spectrometry, and vibrating sample magnetometry. The composite nanoparticles display a strong red emission and superparamagnetic behavior at room temperature. The cell viability and uptake assays reveal good biocompatibility of these hybrid nanoparticles. Hence, the composite nanoparticles are of potential to be further explored as therapeutic vector in biomedical field.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Nanoparticle-Based Drug Delivery · Advanced biosensing and bioanalysis techniques · Supramolecular Self-Assembly in Materials

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

State Key Laboratory of Chemical Resource Engineering, Key Laboratory of Carbon Fiber and Functional Polymers, Ministry of Education, Beijing Laboratory of Biomedical Materials, Beijing University of Chemical Technology, 100029 Beijing, China

Department of Entomology, China Agricultural University, 100193 Beijing, China

Funding

Ministry of Education of the People's Republic of China · National Natural Science Foundation of China · Natural Science Foundation of Beijing Municipality

References (35)

Show source-provided references
1. Corr S. A. · Nanoscale Res. Lett. · 2008 · 3 · 8710.1007/s11671-008-9122-8 ↗
2. Zhang X. · Polym. Chem. · 2014 · 20 · 588510.1039/C4PY00794H ↗
3. Yoon T. J. · Small · 2006 · 2 · 20910.1002/smll.200500360 ↗
4. Sabareesh K. · J. Mater. Chem. · 2012 · 22 · 2064110.1039/c2jm34508k ↗
5. Hsu B. Y. W. · Nanoscale · 2014 · 6 · 29310.1039/C3NR04378A ↗
6. Chen Y. · ACS Nano · 2010 · 4 · 600110.1021/nn1015117 ↗
7. Jordan A. · J. Magn. Magn. Mater. · 2001 · 225 · 11810.1016/S0304-8853(00)01239-7 ↗
8. Kouassi G. K. · Anal. Chem. · 2006 · 78 · 323410.1021/ac051621j ↗
9. Gao J. · J. Am. Chem. Soc. · 2008 · 130 · 371010.1021/ja7103125 ↗
10. Sahu S. · Dalton Trans. · 2013 · 42 · 222410.1039/C2DT31812A ↗
11. Zhang X. · J. Mater. Chem. B · 2014 · 28 · 439810.1039/c4tb00291a ↗
12. Gong X. · J. Mater. Chem. B · 2013 · 1 · 209810.1039/c3tb20061b ↗
13. Tong L. · J. Phys. Chem. C · 2012 · 116 · 715310.1021/jp212579t ↗
14. Huh Y.-M. · J. Am. Chem. Soc. · 2005 · 127 · 1238710.1021/ja052337c ↗
15. Gu H. · Chem. Commun. · 2005 · 427010.1039/b507779f ↗
16. Lee C. S. · Macromol. Biosci. · 2012 · 13 · 32110.1002/mabi.201200308 ↗
17. Zhang Y. · Chem. Mater. · 2013 · 25 · 297610.1021/cm4005618 ↗
18. Yang H. · Adv. Funct. Mater. · 2010 · 20 · 173310.1002/adfm.200902445 ↗
19. Schmidt-Mende L. · Science · 2001 · 293 · 111910.1126/science.293.5532.1119 ↗
20. Zhou R. · Chem. Commun. · 2011 · 47 · 666810.1039/c1cc11200g ↗
21. Yin M. · J. Am. Chem. Soc. · 2008 · 130 · 780610.1021/ja8022362 ↗
22. Kaiser T. E. · J. Am. Chem. Soc. · 2009 · 131 · 671910.1021/ja900684h ↗
23. Xu Z. · Chem. Commun. · 2013 · 49 · 364610.1039/c3cc40330k ↗
24. Yin M. · Small · 2008 · 4 · 89410.1002/smll.200701107 ↗
25. Yin M. · Small · 2011 · 7 · 162910.1002/smll.201100187 ↗
26. Li J. · Small · 2014 · 10 · 135110.1002/smll.201302920 ↗
27. Alhakamy N. A. · Mol. Pharmacol. · 2013 · 10 · 194010.1021/mp3007117 ↗
28. Cui J. · Biomacromolecules · 2013 · 14 · 125110.1021/bm400022h ↗
29. Gujarathi N. A. · Int. J. Pharm. · 2012 · 436 · 41810.1016/j.ijpharm.2012.07.016 ↗
30. Klok H. A. · Macromol. Chem. Phys. · 2002 · 203 · 110610.1002/1521-3935(20020501)203:8<1106::AID-MACP1106>3.0.CO;2-F ↗
31. Sun Y. · Eur. Polym. J. · 2007 · 43 · 76210.1016/j.eurpolymj.2006.10.021 ↗
32. Lu Y. · Nanoscale · 2015 · 7 · 160610.1039/C4NR06104G ↗
33. Zhang Y. · J. Phys. Chem. C · 2008 · 112 · 962310.1021/jp8015326 ↗
34. Yemm E. · Analyst · 1955 · 80 · 20910.1039/an9558000209 ↗
35. Peneva K. · Angew. Chem., Int. Ed. · 2008 · 120 · 342010.1002/ange.200705409 ↗