State-of-the-Art of Nanodiagnostics and Nanotherapeutics against SARS-CoV-2
Source abstract
Abstract
The pandemic outbreak of SARS-CoV-2, with millions of infected patients worldwide, has severely challenged all aspects of public health. In this regard, early and rapid detection of infected cases and providing effective therapeutics against the virus are in urgent demand. Along with conventional clinical protocols, nanomaterial-based diagnostics and therapeutics hold a great potential against coronavirus disease 2019 (COVID-19). Indeed, nanoparticles with their outstanding characteristics would render additional advantages to the current approaches for rapid and accurate diagnosis and also developing prophylactic vaccines or antiviral therapeutics. In this review, besides presenting an overview of the coronaviruses and SARS-CoV-2, we discuss the introduced nanomaterial-based detection assays and devices and also antiviral formulations and vaccines for coronaviruses.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: SARS-CoV-2 detection and testing · SARS-CoV-2 and COVID-19 Research · COVID-19 Clinical Research Studies
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Medical Nanotechnology, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran
Nanomedicine and Nanobiology Research Center, Shiraz University of Medical Sciences, Shiraz Iran
Natural Products and Medicinal Plants Research Center, North Khorasan University of Medical Sciences, Bojnurd, Iran
Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
Funding
Shiraz University of Medical Sciences
References (100+)
Show source-provided references
1. World Health Organization. Coronavirus Disease (Covid-2019) Situation Reports 1-45, 2020, https://www.who.Int/Emergencies/Diseases/Novel-Coronavirus-2019/Situation-Reports.
2. World Health Organization. Laboratory Testing of Human Suspected Cases of Novel Coronavirus (nCoV) Infection, 2020, https://www.who.int/publications/i/item/10665-330374.
3. 10.1038/s41564-020-0695-z10.1038/s41564-020-0695-z ↗
4. WHO. Covid-19 Statistics,https://Covid19.who.int/. 2021.
5. 10.1016/S0140-6736(20)30183-510.1016/S0140-6736(20)30183-5 ↗
6. WHO. Sars-Cov-2 Clinical Symptomes,https://www.who.int/Emergencies/Diseases/Novel-Coronavirus-2019/Question-and-Answers-Hub/Q-a-Detail/Coronavirus-Disease-Covid-19#:~:Text=Symptoms, 2021.
7. 10.1021/acs.bioconjchem.0c0032310.1021/acs.bioconjchem.0c00323 ↗
8. 10.1038/s41565-020-0751-010.1038/s41565-020-0751-0 ↗
9. 10.1021/acsnano.0c0369710.1021/acsnano.0c03697 ↗
10. 10.1039/C7AY00048K10.1039/C7AY00048K ↗
11. 10.1016/j.biotechadv.2016.09.00310.1016/j.biotechadv.2016.09.003 ↗
12. 10.1016/j.aca.2017.06.04510.1016/j.aca.2017.06.045 ↗
13. Younis, S.; Taj, A.; Zia, R.; Hayat, H.; Shaheen, A.; Awan, F. R.; Bhatti, H. N.; Khan, W. S.; Bajwa, S. Z. Nanosensors for the Detection of Viruses. In Nanosensors for Smart Cities; Han, B., Tomer, V. K., Nguyen, T. A., Farmani, A., Kumar Singh, P., Eds. Elsevier, 2020; Chapter 19, pp 327–338.10.1016/B978-0-12-819870-4.00018-9 ↗
14. 10.7150/thno.2385610.7150/thno.23856 ↗
15. Zehbe I. · Am. J. Pathol. · 1997 · 150 · 1553
16. 10.1016/j.colsurfb.2019.02.02510.1016/j.colsurfb.2019.02.025 ↗
17. 10.1016/j.jelechem.2019.04.04510.1016/j.jelechem.2019.04.045 ↗
18. 10.1021/acsnano.5b0562210.1021/acsnano.5b05622 ↗
19. 10.1007/s00604-017-2300-610.1007/s00604-017-2300-6 ↗
20. 10.1016/j.nano.2013.11.00910.1016/j.nano.2013.11.009 ↗
21. 10.1016/j.trac.2017.10.00510.1016/j.trac.2017.10.005 ↗
22. 10.1007/s13205-019-1577-z10.1007/s13205-019-1577-z ↗
23. 10.1021/acs.chemrev.5b0010910.1021/acs.chemrev.5b00109 ↗
24. 10.3389/fimmu.2019.0002210.3389/fimmu.2019.00022 ↗
25. 10.1021/acsami.6b0334210.1021/acsami.6b03342 ↗
26. 10.1021/am405040z10.1021/am405040z ↗
27. 10.1021/acsami.6b0168110.1021/acsami.6b01681 ↗
28. 10.1021/acsami.9b1503210.1021/acsami.9b15032 ↗
29. 10.1038/pj.2014.4010.1038/pj.2014.40 ↗
30. Summary of Probable Sars Cases with Onset of Illness from 1 November 2002 to 31 July 2003, https://www.who.int/Csr/Sars/Country/Table2004_04_21/En/, 2003.
31. 10.1186/s12985-015-0422-110.1186/s12985-015-0422-1 ↗
32. 10.1126/science.111839110.1126/science.1118391 ↗
33. 10.1073/pnas.050673510210.1073/pnas.0506735102 ↗
34. 10.1038/s41586-020-2012-710.1038/s41586-020-2012-7 ↗
35. 10.3390/v1103021010.3390/v11030210 ↗
36. 10.1128/JVI.00645-0610.1128/JVI.00645-06 ↗
37. 10.1038/nrmicro209010.1038/nrmicro2090 ↗
38. 10.1088/1752-7163/aba10510.1088/1752-7163/aba105 ↗
39. 10.1021/acscentsci.0c0027210.1021/acscentsci.0c00272 ↗
40. 10.1038/s41569-020-0360-510.1038/s41569-020-0360-5 ↗
41. 10.1126/science.abb250710.1126/science.abb2507 ↗
42. 10.1038/nature1200510.1038/nature12005 ↗
43. 10.1073/pnas.030644610110.1073/pnas.0306446101 ↗
44. 10.3390/v1109083710.3390/v11090837 ↗
45. 10.1073/pnas.080952410610.1073/pnas.0809524106 ↗
46. 10.1074/jbc.M110.10327510.1074/jbc.M110.103275 ↗
47. 10.1016/j.antiviral.2020.10474210.1016/j.antiviral.2020.104742 ↗
48. 10.1038/cr.2008.1510.1038/cr.2008.15 ↗
49. 10.1016/j.pharmthera.2010.06.00310.1016/j.pharmthera.2010.06.003 ↗
50. 10.1038/s41565-020-0674-910.1038/s41565-020-0674-9 ↗
51. 10.12688/f1000research.19694.110.12688/f1000research.19694.1 ↗
52. 10.1016/S0065-3527(06)66005-310.1016/S0065-3527(06)66005-3 ↗
53. 10.1128/IAI.73.4.1907-1916.200510.1128/IAI.73.4.1907-1916.2005 ↗
54. 10.1038/s41577-020-0311-810.1038/s41577-020-0311-8 ↗
55. 10.1073/pnas.040906510210.1073/pnas.0409065102 ↗
56. 10.1021/acsnano.0c0400610.1021/acsnano.0c04006 ↗
57. 10.1016/j.cell.2006.02.01510.1016/j.cell.2006.02.015 ↗
58. 10.1146/annurev.biochem.74.082803.13334710.1146/annurev.biochem.74.082803.133347 ↗
59. 10.1016/j.virol.2015.02.01710.1016/j.virol.2015.02.017 ↗
60. 10.1128/JVI.01464-1010.1128/JVI.01464-10 ↗
61. 10.1016/S2213-2600(20)30076-X10.1016/S2213-2600(20)30076-X ↗
62. 10.1002/jmv.2568510.1002/jmv.25685 ↗
63. 10.1056/NEJM20030731349052010.1056/NEJM200307313490520 ↗
64. 10.1001/jama.2020.478310.1001/jama.2020.4783 ↗
65. 10.1172/JCI13800310.1172/JCI138003 ↗
66. 10.1016/j.isci.2020.10140610.1016/j.isci.2020.101406 ↗
67. 10.1007/s40820-020-00533-y10.1007/s40820-020-00533-y ↗
68. 10.1021/acsabm.0c0154510.1021/acsabm.0c01545 ↗
69. Corman, V.; Bleicker, T.; Brünink, S.; Drosten, C. Diagnostic Detection of 2019-Ncov by Real-Time RT-PCR, https://www.who.int/docs/default-source/coronaviruse/protocol-v2-1.pdf?sfvrsn=a9ef618c_2, 2020.
70. 10.2807/1560-7917.es.2020.25.3.200004510.2807/1560-7917.es.2020.25.3.2000045 ↗
71. WHO. Real-Time RT-PCR Panel for Detection 2019-Novel Coronavirus,www.who.int/Docs/Default-Source/Coronaviruse/Uscdcrt-Pcr-Panel-for-Detection-Instructions.Pdf?Sfvrsn=3aa07934_2, 2020.
72. 10.1093/infdis/jiaa22910.1093/infdis/jiaa229 ↗
73. 10.1001/jama.2020.825910.1001/jama.2020.8259 ↗
74. 10.7326/M20-050410.7326/M20-0504 ↗
75. 10.1101/2020.03.24.2004268910.1101/2020.03.24.20042689 ↗
76. 10.1148/radiol.202020046310.1148/radiol.2020200463 ↗
77. 10.1007/s00330-020-06731-x10.1007/s00330-020-06731-x ↗
78. 10.1039/C4AN01079E10.1039/C4AN01079E ↗
79. 10.1146/annurev.physchem.040808.09043410.1146/annurev.physchem.040808.090434 ↗
80. 10.1007/s00216-007-1768-z10.1007/s00216-007-1768-z ↗
81. 10.22034/NMRJ.2018.04.00310.22034/NMRJ.2018.04.003 ↗
82. 10.1049/iet-nbt.2017.014410.1049/iet-nbt.2017.0144 ↗
83. 10.1021/acssensors.6b0076310.1021/acssensors.6b00763 ↗
84. 10.1002/jmv.2572710.1002/jmv.25727 ↗
85. WHO. Antigen-Detection in the Diagnosis of Sars-Cov-2 Infection Using Rapid Immunoassays, https://www.who.int/publications/i/item/antigen-detection-in-the-diagnosis-of-sars-cov-2infection-using-rapid-immunoassays, 2020.
86. 10.1039/D0RA04107F10.1039/D0RA04107F ↗
87. 10.1039/D0AN00629G10.1039/D0AN00629G ↗
88. 10.1021/acsomega.0c0155410.1021/acsomega.0c01554 ↗
89. 10.1021/acscentsci.0c0085510.1021/acscentsci.0c00855 ↗
90. 10.1073/pnas.171259211410.1073/pnas.1712592114 ↗
91. 10.1039/C9TB02004G10.1039/C9TB02004G ↗
92. 10.1039/c2cs35427f10.1039/c2cs35427f ↗
93. 10.1021/ac034256+10.1021/ac034256+ ↗
94. 10.1128/CVI.00218-0710.1128/CVI.00218-07 ↗
95. 10.1039/c3ra47398h10.1039/c3ra47398h ↗
96. 10.1016/j.clinbiochem.2010.07.00110.1016/j.clinbiochem.2010.07.001 ↗
97. 10.1021/acs.analchem.7b0025510.1021/acs.analchem.7b00255 ↗
98. 10.1021/acssensors.9b0017510.1021/acssensors.9b00175 ↗
99. 10.1021/acsnano.0c0382210.1021/acsnano.0c03822 ↗
100. 10.1021/acssensors.0c0174210.1021/acssensors.0c01742 ↗