DataVXACS Applied Materials & InterfacesPaper
journal article·2016-10-05

Hyaluronic Acid-Coated Silver Nanoparticles As a Nanoplatform for in Vivo Imaging Applications

Xin Zhang, Meinan Yao, Muhua Chen, Liqiang Li, Chengyan Dong, Yi Hou, Huiyun Zhao, Bing Jia, Fan Wang

ACS Applied Materials & Interfaces· Volume 8· Issue 39
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Source abstract

Abstract

An efficient chemical reduction protocol has been developed for the synthesis of hyaluronic acid-coated silver nanoparticles (HA-Ag NPs) that are spherical, ultrasmall and monodisperse. The as-synthesized HA-Ag NPs not only exhibited excellent long-term stability and low cytotoxicity but also could be used as a nanoplatform for X-ray computed tomography (CT) and single-photon emission computed tomography (SPECT) imaging after being radiolabeled with 99m Tc.
Source: openalex_inverted_index · Quality: baseline

Research context

Nanomaterials

OpenAlex topics: Nanocluster Synthesis and Applications · Gold and Silver Nanoparticles Synthesis and Applications · Nanoplatforms for cancer theranostics

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Medical Isotopes Research Center and Department of Radiation Medicine, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China

Key Laboratory of Protein and Peptide Pharmaceuticals, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China

Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China

Medical and Healthy Analytical Center, Peking University, Beijing 100191, China

Funding

National Natural Science Foundation of China · Chinese Academy of Sciences · Beijing Ministry of Science and Technology

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