Polystyrene Nanofiber Materials for Visible-Light-Driven Dual Antibacterial Action via Simultaneous Photogeneration of NO and O2(1Δg)
Source abstract
Abstract
This contribution reports on the preparation, characterization, and biological evaluation of electrospun polystyrene nanofiber materials engineered with a covalently grafted NO photodonor and ionically entangled tetracationic porphyrin and phthalocyanine photosensitizers. These photofunctional materials exhibit an effective and simultaneous photogeneration of two antibacterial species such as nitric oxide (NO) and singlet oxygen, O2((1)Δg) under illumination with visible light, as demonstrated by their direct detection using amperometric and time-resolved spectroscopic techniques. Dual-mode photoantibacterial action is demonstrated by antibacterial tests carried out on Escherichia coli.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Nanoplatforms for cancer theranostics · Photodynamic Therapy Research Studies · Porphyrin and Phthalocyanine Chemistry
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Faculty of Science, Charles University in Prague, 2030 Hlavova, 128 43 Prague 2, Czech Republic
Institute of Inorganic Chemistry, v.v.i., Czech Academy of Sciences, 250 68 Řež, Czech Republic
J. Heyrovský Institute of Physical Chemistry, v.v.i., Czech Academy of Sciences, Dolejškova 3, 182 23 Prague 8, Czech Republic
Laboratory of Photochemistry, Department of Drug Sciences, University of Catania, Viale Andrea Doria 6, I-95125 Catania, Italy
Funding
Ministero dell'Istruzione, dell'Università e della Ricerca · Czech Science Foundation
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