Boronic Acid-Functionalized Particles with Flexible Three-Dimensional Polymer Branch for Highly Specific Recognition of Glycoproteins
Source abstract
Abstract
A novel organic-inorganic hybrid particle with high hydrophilicity three-dimensional boronic acid functional polymer branches was facilely synthesized through thiol-ene surface-initiated click reaction, by which the target glycoprotein could be captured selectively in the 5000-fold disrupting protein. This highest selectivity ever reported demonstrated that this boronic acid functionalized particle exhibited great potential in the recognition of cis-diol-containing biomolecules, including the glycoproteins.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Glycosylation and Glycoproteins Research · Advanced biosensing and bioanalysis techniques · Analytical Chemistry and Chromatography
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
National Chromatographic R. & A. Center, Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China
College of Environment Science and Engineering, Fujian Normal University, Fuzhou, Fujian 350007, China
Funding
National Natural Science Foundation of China · Ministry of Science and Technology
References (19)
Show source-provided references
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