DataVXACS Applied Materials & InterfacesPaper
journal article·2018-01-10

Organic-Dye-Modified Upconversion Nanoparticle as a Multichannel Probe To Detect Cu2+ in Living Cells

Bin Gu, Minan Ye, Lina Nie, Yuan Fang, Zilong Wang, Xiao Zhang, Hua Zhang, Yi Zhou, Qichun Zhang

ACS Applied Materials & Interfaces· Volume 10· Issue 1
Publisher page
Source abstract

Abstract

The development of an inorganic–organic hybrid probe to more accurately detect ions in living systems is very challenging but highly desirable. Here we combined upconversion nanoparticles with the electrically active ferrocene group to detect Cu 2+ in living cells. The as-prepared probe displays three different signal changes in absorption, emission, and electrochemical behavior, respectively, during Cu 2+ ion detection. Moreover, this new probe has been demonstrated to show high stability and adaptability. In addition, bioimaging testing reveals that this probe is suitable for detecting and visualizing Cu 2+ in A549 cells with low cytotoxicity.
Source: openalex_inverted_index · Quality: baseline

Research context

Nanomaterials

OpenAlex topics: Luminescence Properties of Advanced Materials · bioluminescence and chemiluminescence research · Luminescence and Fluorescent Materials

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

School of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Avenue 639798, Singapore

College of Chemistry and Molecular Engineering, Nanjing Tech University, Nanjing 211816, P. R. China

Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link 637371, Singapore

Funding

Ministry of Education - Singapore · Natural Science Foundation of Jiangsu Province · Jiangsu Province · Key Laboratory of Supramolecular Structure and Materials, Jilin University

References (35)

Show source-provided references
1. 10.1038/ng0193-710.1038/ng0193-7 ↗
2. 10.1021/bi801926e10.1021/bi801926e ↗
3. 10.1021/ja800868a10.1021/ja800868a ↗
4. 10.1002/anie.20070452010.1002/anie.200704520 ↗
5. 10.1039/C1CS15187H10.1039/C1CS15187H ↗
6. 10.1002/anie.20100515910.1002/anie.201005159 ↗
7. 10.1021/ac802072d10.1021/ac802072d ↗
8. 10.1021/ac901960d10.1021/ac901960d ↗
9. 10.1038/nature0877710.1038/nature08777 ↗
10. 10.1016/j.biomaterials.2010.01.04010.1016/j.biomaterials.2010.01.040 ↗
11. 10.1016/j.biomaterials.2009.05.06210.1016/j.biomaterials.2009.05.062 ↗
12. 10.1021/ja076151k10.1021/ja076151k ↗
13. 10.1006/abio.1998.296510.1006/abio.1998.2965 ↗
14. 10.1039/C4CS00173G10.1039/C4CS00173G ↗
15. 10.1002/smll.20140186710.1002/smll.201401867 ↗
16. 10.1016/j.biomaterials.2010.09.06910.1016/j.biomaterials.2010.09.069 ↗
17. 10.1016/j.biomaterials.2011.08.03810.1016/j.biomaterials.2011.08.038 ↗
18. 10.1016/j.biomaterials.2010.05.06510.1016/j.biomaterials.2010.05.065 ↗
19. 10.1021/ja403798m10.1021/ja403798m ↗
20. 10.1021/ja511524810.1021/ja5115248 ↗
21. 10.1021/ja210077410.1021/ja2100774 ↗
22. 10.1021/ja306066a10.1021/ja306066a ↗
23. 10.1021/jacs.5b0150410.1021/jacs.5b01504 ↗
24. 10.1002/anie.20150000810.1002/anie.201500008 ↗
25. 10.1016/j.biomaterials.2014.10.06610.1016/j.biomaterials.2014.10.066 ↗
26. 10.1039/c2cc31642k10.1039/c2cc31642k ↗
27. 10.1039/C5CC04750A10.1039/C5CC04750A ↗
28. 10.1016/j.jlumin.2013.07.02110.1016/j.jlumin.2013.07.021 ↗
29. 10.1039/C4NR04380D10.1039/C4NR04380D ↗
30. 10.1016/j.biomaterials.2015.03.00310.1016/j.biomaterials.2015.03.003 ↗
31. 10.1002/smll.20130312710.1002/smll.201303127 ↗
32. 10.1039/C5NR05286F10.1039/C5NR05286F ↗
33. 10.1021/acs.organomet.5b0028510.1021/acs.organomet.5b00285 ↗
34. 10.1016/j.snb.2017.03.09210.1016/j.snb.2017.03.092 ↗
35. 10.1039/C5NJ03010B10.1039/C5NJ03010B ↗