journal article·2015-05-27

Antimicrobial and Osteogenic Properties of Silver-Ion-Implanted Stainless Steel

Hui Qin, Huiliang Cao, Yaochao Zhao, Guodong Jin, Mengqi Cheng, Jiaxin Wang, Yao Jiang, Zhiquan An, Xianlong Zhang, Xuanyong Liu

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Abstract

Prevention of implant loosening and infection is crucial to orthopedic and dental surgeries. In this work, the surface of stainless steel (SS) was modified by silver-sourced plasma immersion ion implantation (Ag-PIII). Metallic silver nanoparticles with various diameters and distributions were fabricated on the SS surfaces after treatment with Ag-PIII for 0.5 and 1.5 h, respectively. The osteogenic activity and antimicrobial properties of SS before and after Ag-PIII treatment were evaluated using in vitro and in vivo tests. The results demonstrated that Ag-PIII treatment not only promoted the antibacterial activity of SS but also enhanced the osteogenic differentiation of human bone marrow stromal cells.
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Research context

OpenAlex topics: Ion-surface interactions and analysis · Metal and Thin Film Mechanics · Bone Tissue Engineering Materials

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Orthopedics, Shanghai Sixth People’s Hospital, Shanghai Jiao Tong University, Shanghai 200233, China

State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China

Funding

Ministry of Science and Technology of the People's Republic of China · Science and Technology Commission of Shanghai Municipality · National Natural Science Foundation of China · Chinese Academy of Sciences · Science and Technology Committee of Shanghai Municipality · State Key Laboratory of High Performance Ceramics and Superfine Microstructure

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