Selectively Regulating the Chiral Morphology of Amino Acid-Assisted Chiral Gold Nanoparticles with Circularly Polarized Light

Chiral nanomaterials have attracted increasing attention due to their versatile optical properties. Although circularly polarized (CP) light can serve as an inducer, it has negligible effects because of the short lifetime of the plasmonic states. Here, we propose that the site-selective chirality regulation on the morphology of cysteine (cys) amino acid-assisted chiral gold nanoparticles (cys-chiral AuNPs) can be realized through CP light irradiation. This can result in the increased or decreased circular dichroism (CD) signal intensity. The site-selective growth mechanism of the cys-chiral AuNPs is elucidated with light-matter interactions through the opposite rotation of right(R)/left(L) CP light. The site-selective chirality growth of the cys-chiral AuNPs is ascribed to the morphology evolution induced by the synergy of cys and R/L-CP light, which is clearly analyzed and elucidated with high CD intensities. This work provides a promising alternative strategy to produce high-chirality nanomaterials that can be applied in biomedicine and enantiomer photocatalytic reaction.