DataVXACS Applied Materials & InterfacesPaper
journal article·2023-07-26

Direct Laser Writing of the Porous Graphene Foam for Multiplexed Electrochemical Sweat Sensors

Li Yang, He Wang, Abu Musa Abdullah, Chuizhou Meng, Xue Chen, Anqi Feng, Huanyu Cheng

ACS Applied Materials & Interfaces· Volume 15· Issue 29
Publisher page
Source abstract

Abstract

Wearable electrochemical sensors provide means to detect molecular-level information from the biochemical markers in biofluids for physiological health evaluation. However, a high-density array is often required for multiplexed detection of multiple markers in complex biofluids, which is challenging with low-cost fabrication methods. This work reports the low-cost direct laser writing of porous graphene foam as a flexible electrochemical sensor to detect biomarkers and electrolytes in sweat. The resulting electrochemical sensor exhibits high sensitivity and low limit of detection for various biomarkers (e.g., the sensitivity of 6.49/6.87/0.94/0.16 μA μM –1 cm –2 and detection limit of 0.28/0.26/1.43/11.3 μM to uric acid/dopamine/tyrosine/ascorbic acid) in sweat. The results from this work open up opportunities for noninvasive continuous monitoring of gout, hydration status, and drug intake/overdose.
Source: openalex_inverted_index · Quality: baseline

Research context

Energy storageNanomaterials

OpenAlex topics: Advanced Sensor and Energy Harvesting Materials · Gas Sensing Nanomaterials and Sensors · Analytical Chemistry and Sensors

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

State Key Laboratory of Reliability and Intelligence of Electrical Equipment, School of Health Sciences and Biomedical Engineering, Hebei University of Technology, Tianjin 300130, China

Department of Engineering Science and Mechanics, The Pennsylvania State University, University Park, Pennsylvania 16802, United States

State Key Laboratory for Reliability and Intelligence of Electrical Equipment, Hebei Key Laboratory of Smart Sensing and Human-Robot Interaction, School of Mechanical Engineering, Hebei University of Technology, Tianjin 300401, China

State Key Laboratory of Reliability and Intelligence of Electrical Equipment, Key Laboratory of Bioelectromagnetics and Neuroengineering of Hebei Province, School of Electrical Engineering, Hebei University of Technology, Tianjin 300130, China

Funding

National Heart, Lung, and Blood Institute · China Postdoctoral Science Foundation · National Institute of Biomedical Imaging and Bioengineering · Hebei Provincial Key Research Projects · Pennsylvania State University · Division of Electrical, Communications and Cyber Systems · National Institute on Drug Abuse · National Natural Science Foundation of China

References (71)

Show source-provided references
1. 10.1038/s41928-018-0043-y10.1038/s41928-018-0043-y ↗
2. 10.1038/s41928-021-00556-210.1038/s41928-021-00556-2 ↗
3. 10.1038/s41586-021-03772-010.1038/s41586-021-03772-0 ↗
4. 10.1002/adfm.20220092210.1002/adfm.202200922 ↗
5. 10.1016/j.bios.2021.11307810.1016/j.bios.2021.113078 ↗
6. 10.1124/jpet.107.12903110.1124/jpet.107.129031 ↗
7. 10.1038/s41587-019-0321-x10.1038/s41587-019-0321-x ↗
8. 10.1038/s41551-022-00916-z10.1038/s41551-022-00916-z ↗
9. 10.1111/cns.1276710.1111/cns.12767 ↗
10. 10.1038/nature1652110.1038/nature16521 ↗
11. 10.1016/j.bios.2022.11426410.1016/j.bios.2022.114264 ↗
12. 10.1111/j.2042-7158.1973.tb10042.x10.1111/j.2042-7158.1973.tb10042.x ↗
13. 10.1073/pnas.200997911710.1073/pnas.2009979117 ↗
14. 10.3390/chemosensors1011044610.3390/chemosensors10110446 ↗
15. 10.1016/j.cej.2022.13504710.1016/j.cej.2022.135047 ↗
16. 10.1007/s00604-021-05024-410.1007/s00604-021-05024-4 ↗
17. 10.1016/j.bios.2021.11360610.1016/j.bios.2021.113606 ↗
18. 10.1016/j.snb.2020.12786610.1016/j.snb.2020.127866 ↗
19. 10.1016/j.bios.2020.11222010.1016/j.bios.2020.112220 ↗
20. 10.1016/j.jhazmat.2020.12377410.1016/j.jhazmat.2020.123774 ↗
21. 10.1038/ncomms1165010.1038/ncomms11650 ↗
22. 10.1021/ac401573r10.1021/ac401573r ↗
23. 10.1021/acssensors.0c0244610.1021/acssensors.0c02446 ↗
24. 10.1007/s00216-020-02939-410.1007/s00216-020-02939-4 ↗
25. 10.1126/sciadv.aax064910.1126/sciadv.aax0649 ↗
26. 10.1126/sciadv.aaw990610.1126/sciadv.aaw9906 ↗
27. 10.1021/acsnano.8b0250510.1021/acsnano.8b02505 ↗
28. 10.1021/acs.nanolett.2c0150010.1021/acs.nanolett.2c01500 ↗
29. 10.1109/JSEN.2021.307328710.1109/JSEN.2021.3073287 ↗
30. 10.3390/nano1203042110.3390/nano12030421 ↗
31. 10.1016/j.colsurfb.2014.09.00510.1016/j.colsurfb.2014.09.005 ↗
32. 10.1016/j.snb.2015.12.03210.1016/j.snb.2015.12.032 ↗
33. 10.1039/D1ME00130B10.1039/D1ME00130B ↗
34. 10.1021/acsami.2c0206110.1021/acsami.2c02061 ↗
35. 10.1016/j.nanoen.2022.10760610.1016/j.nanoen.2022.107606 ↗
36. 10.1038/s41378-022-00414-x10.1038/s41378-022-00414-x ↗
37. 10.1039/C9TA07855J10.1039/C9TA07855J ↗
38. 10.1016/j.cej.2022.13663110.1016/j.cej.2022.136631 ↗
39. 10.1016/j.nanoen.2022.10780710.1016/j.nanoen.2022.107807 ↗
40. 10.1016/j.snb.2021.13067410.1016/j.snb.2021.130674 ↗
41. 10.1021/acsami.1c0561410.1021/acsami.1c05614 ↗
42. 10.1007/s12274-021-3441-910.1007/s12274-021-3441-9 ↗
43. 10.1016/j.susmat.2020.e0020510.1016/j.susmat.2020.e00205 ↗
44. 10.1063/5.002450810.1063/5.0024508 ↗
45. 10.1002/adfm.20190445710.1002/adfm.201904457 ↗
46. 10.1038/ncomms671410.1038/ncomms6714 ↗
47. 10.1021/acsami.8b1669210.1021/acsami.8b16692 ↗
48. 10.1016/j.matlet.2019.12715010.1016/j.matlet.2019.127150 ↗
49. 10.1021/acsami.0c1172510.1021/acsami.0c11725 ↗
50. 10.1109/EMBC.2014.694392910.1109/EMBC.2014.6943929 ↗
51. 10.1016/S0278-5919(05)70165-410.1016/S0278-5919(05)70165-4 ↗
52. 10.1016/j.sna.2021.11332010.1016/j.sna.2021.113320 ↗
53. 10.1073/pnas.170174011410.1073/pnas.1701740114 ↗
54. 10.1016/j.tiv.2010.06.01610.1016/j.tiv.2010.06.016 ↗
55. 10.1016/j.surfcoat.2019.01.02510.1016/j.surfcoat.2019.01.025 ↗
56. 10.1016/j.jaap.2016.08.00710.1016/j.jaap.2016.08.007 ↗
57. 10.1016/j.bioelechem.2021.10787010.1016/j.bioelechem.2021.107870 ↗
58. 10.1016/j.talanta.2022.12331910.1016/j.talanta.2022.123319 ↗
59. 10.1073/pnas.160609711310.1073/pnas.1606097113 ↗
60. 10.1016/j.jelechem.2015.10.01210.1016/j.jelechem.2015.10.012 ↗
61. 10.1016/j.talanta.2015.02.03810.1016/j.talanta.2015.02.038 ↗
62. 10.1002/aelm.20160018510.1002/aelm.201600185 ↗
63. 10.1016/j.bios.2018.06.04910.1016/j.bios.2018.06.049 ↗
64. 10.1021/acssuschemeng.9b0596810.1021/acssuschemeng.9b05968 ↗
65. 10.1016/j.carbon.2022.06.01310.1016/j.carbon.2022.06.013 ↗
66. 10.1023/A:102163720956410.1023/A:1021637209564 ↗
67. 10.1007/s00604-021-04792-310.1007/s00604-021-04792-3 ↗
68. 10.1021/ac60230a01610.1021/ac60230a016 ↗
69. 10.1007/BF0042120210.1007/BF00421202 ↗
70. 10.1007/BF0042329210.1007/BF00423292 ↗
71. 10.1371/journal.pone.022338110.1371/journal.pone.0223381 ↗