Solvent-Responsive Molecularly Imprinted Nanogels for Targeted Protein Analysis in MALDI-TOF Mass Spectrometry
Source abstract
Abstract
Molecular imprinted poly(acrylamido)-derivative nanogels have shown their selectivity to bind the protein human serum transferrin (HTR) and also showed their capability for instantaneous solvent-induced modification upon the addition of acetonitrile. Integrated to matrix-assisted laser desorption/ionization time-of-flight mass analysis the HTR-imprinted solvent-responsive nanogels permitted the determination of HTR straight from serum and offered novel perspectives in targeted protein analysis.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Mass Spectrometry Techniques and Applications · Analytical chemistry methods development · Microfluidic and Capillary Electrophoresis Applications
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Physics, University of Trento, Via Sommarive 14, 38123 Trento, Italy
Department of Biotechnology, University of Verona, Strada Le Grazie 15, 37134 Verona, Italy
Department of Molecular Sciences and Nanosystems, University Cà Foscari Venezia, Via Torino 155/b, 30173 Venice, Italy
Department of Diagnostics and Public Health, Unit of Forensic Medicine, University of Verona, P.le L.A. Scuro 10, 37134 Verona, Italy
Fondazione Bruno Kessler CMM-MNF, Via Sommarive 18, 38123 Trento, Italy
Funding
Ministero dell?Istruzione, dell?Universit? e della Ricerca
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